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May 2021 in “Dermatologic Therapy” Possible link between androgens and COVID-19 severity; more research needed.
December 2014 in “대한피부미용학회지” Natural hair-loss preventers from plants and herbs are becoming popular due to fewer side effects and added benefits.
January 2005 in “Urologia Journal” 5αR inhibitors help slow early prostate cancer cell growth, suggesting combined treatments are needed.
May 2023 in “International journal of pharmaceutical sciences and medicine” Sunflower oil was found to promote hair growth in mice with hormone-induced hair loss.
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March 1999 in “Comparative Haematology International” Androgens increase EPO production, finasteride doesn't significantly impact it.
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November 2013 in “PLOS ONE” Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
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November 2004 in “Bioorganic & Medicinal Chemistry Letters” New compounds were made that effectively block enzymes related to prostate issues and hair loss.
May 2023 in “Problems of Endocrinology” Men with high testosterone may have higher morning blood pressure, unlike those with high DHT.
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July 2020 in “Frontiers in immunology” Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
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October 2004 in “Experimental Gerontology” Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.
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October 2016 in “Clinics in Dermatology” Hormonal treatments can improve acne, but they come with potential side effects and risks.
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September 2025 in “Frontiers in Endocrinology” SARMs show promise but need more evidence to prove they're better than traditional androgens.
January 2024 in “Biological & clinical sciences research journal” Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.
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March 2001 in “Journal of Endocrinology/Journal of endocrinology” Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
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March 2001 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Key enzymes control androgen levels, affecting hormone activity and potential treatments.
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July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
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January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
February 2021 in “Медико-фармацевтический журнал "Пульс"” Understanding WNT signaling proteins can help predict and treat certain types of hair loss.
April 2023 in “Dermatologica Sinica” Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.
74 citations
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November 1975 in “Archives of dermatology” Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.
January 2025 in “Dermatologic Therapy” Targeting multiple pathways may improve treatments for androgenetic alopecia.
March 2005 in “Journal of The American Academy of Dermatology” Herbal extract improves hair growth in female pattern baldness.
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January 2004 in “Journal of medicinal chemistry” Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
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March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
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February 2014 in “Planta Medica” Scutellaria baicalensis extract and baicalin may help prevent hair loss.
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