April 2024 in “International journal of clinical trials” SesZen-Bio™ improves hair density, thickness, and overall hair health.
5 citations
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February 2008 in “Experimental Dermatology” Cyclosporin A promotes hair growth in mice and increases a protein linked to hair growth, but it may not work the same way in humans.
January 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.
16 citations
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May 2006 in “PubMed” Alpha-melanocyte-stimulating hormone helps manage skin inflammation and protect against UV damage.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Saw Palmetto, especially with Lycopene, L-Arginine, and Astaxanthin, improves male health by balancing hormones and boosting energy.
6 citations
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August 2014 in “Toxicologic pathology” Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
March 1998 in “Journal of dermatological science” Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.
13 citations
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January 1953 in “Archives of Dermatology” Certain unsaturated compounds can cause temporary hair loss by affecting hair structure.
November 2025 in “ACS Applied Materials & Interfaces” Plant-derived nanovesicles effectively deliver finasteride for hair regrowth in androgenetic alopecia.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.
2 citations
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August 2019 in “PubMed” A specific enzyme that activates the hair growth medication minoxidil when applied to the skin was identified.
January 2026 in “Applied Sciences” Cyclic ADP-ribose helps regulate calcium and signals that promote hair growth in hair follicle cells.
July 2025 in “Current Issues in Molecular Biology” Bio-Pulsed sEVs improve hair growth and skin rejuvenation.
December 2024 in “Pharmaceutics” Spironolactone nano-formulations show promise for treating skin disorders, but more research is needed for safety and effectiveness.
25 citations
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January 2017 in “Steroids” Allopregnanolone increases growth and changes gene activity in human brain cancer cells.
February 2024 in “Biomedical journal of scientific & technical research” Inositol and phytic acid together increase hair growth and density.
1 citations
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April 2016 in “Journal of lipid research” Lipin-1 is important for skin cell differentiation and skin barrier function.
April 2011 in “HAL (Le Centre pour la Communication Scientifique Directe)” Chitosan-decorated nanoparticles improve skin delivery of finasteride, with PS404-b-PAA63 being most effective.
Trichoriboside treatment helps maintain scalp hair by increasing cAMP levels in hair follicles of men with hair loss.
1 citations
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January 2025 in “Frontiers in Pharmacology” Total glucosides of paeony can help treat skin conditions but need more research for clinical use.
April 2016 in “Journal of Investigative Dermatology” Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
11 citations
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March 2009 in “Bioorganic & Medicinal Chemistry Letters” Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.
38 citations
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January 2017 in “PPAR Research” PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
83 citations
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May 2011 in “European Journal of Dermatology” Corneodesmosin is crucial for skin and hair health, and its dysfunction can cause skin and hair disorders.
21 citations
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March 2021 in “Molecules” The new formulation greatly improved quercetin absorption in rats.
84 citations
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April 2013 in “Applied Microbiology and Biotechnology” Mannosylerythritol lipids are good for skin and hair care products.
10 citations
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May 2021 in “Expert Opinion on Drug Delivery” Coenzyme Q10 vesicular formulations can potentially treat androgenic alopecia by promoting hair growth and thickness.
11 citations
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January 2020 in “Engineered science” Combining β-sitosterol nanoparticles with laser therapy may effectively stimulate hair growth in androgenetic alopecia.