46 citations
,
December 2006 in “Anais Brasileiros de Dermatologia” Acne is the most common skin problem in Brazil, with a need for improved dermatological care and health education, especially for the public sector and black-skinned individuals.
45 citations
,
November 1979 in “British Journal of Dermatology” Minoxidil causes excessive hair growth in almost all patients.
43 citations
,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
43 citations
,
October 2005 in “Molecular and cellular endocrinology” Hair melanocytes help the skin respond to stress and regulate hair pigmentation.
41 citations
,
September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
41 citations
,
April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
38 citations
,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
37 citations
,
June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
34 citations
,
October 2015 in “British journal of dermatology/British journal of dermatology, Supplement” Scientists don't fully understand eyelash hair follicle biology, including growth and color, and suggest more research is needed.
34 citations
,
December 1988 in “Pigment Cell Research” Melanocytes appear in fetal skin early, but their development details are still unclear.
32 citations
,
June 2013 in “Journal of Investigative Dermatology” Mice without certain skin proteins had abnormal skin and hair development.
32 citations
,
August 2003 in “Journal of the European Academy of Dermatology and Venereology” cGVHD often severely affects the skin, causing rapid aging and other issues.
31 citations
,
April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
31 citations
,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
30 citations
,
November 2019 in “Genetics selection evolution” Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.
30 citations
,
June 2006 in “British journal of dermatology/British journal of dermatology, Supplement” Oral zinc sulphate reduces dark hair color in mice.
29 citations
,
June 2016 in “Experimental Dermatology” MCHR2 gene duplications may be linked to alopecia areata.
29 citations
,
January 2013 in “International Journal of Medical Sciences” Wnt10b helps hair follicle cells mature and produce pigment.
29 citations
,
March 2011 in “The Journal of Nutritional Biochemistry” Eating isoflavone can help mice grow hair by increasing a growth factor.
29 citations
,
February 2011 in “PloS one” Astressin-B can reverse and prevent hair loss in stressed mice.
29 citations
,
June 1998 in “Developmental Biology” More melanoblasts in hair follicles mean better survival and proper hair pigmentation.
28 citations
,
May 2017 in “Molecular ecology” Researchers found genes that control hair color and growth change before the visible coat color changes in snowshoe hares.
24 citations
,
March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
23 citations
,
November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
22 citations
,
September 2019 in “Trends in Immunology” Acne is a temporary skin imbalance during puberty that often resolves on its own.
21 citations
,
December 2023 in “Journal of Investigative Dermatology” Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
20 citations
,
March 2021 in “Drug design, development and therapy” Topical immunotherapy can treat alopecia areata, but its effectiveness varies and the exact mechanism is unclear.
19 citations
,
August 2020 in “Gastroenterology report” There is no standard treatment for the rare Cronkhite–Canada syndrome, which can be fatal and lead to cancer.
18 citations
,
January 2020 in “Ecology and evolution” Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
18 citations
,
October 2023 in “Nature Communications” Men with baldness are more prone to skin cancers on the scalp due to sun exposure, not testosterone.