February 2010 in “Journal of The American Academy of Dermatology” A woman's nail separation was likely caused by poor blood flow, and a treatment for similar conditions might help.
8 citations
,
May 2005 in “The American journal of dermatopathology/American journal of dermatopathology” The hair defect is due to abnormal inner root sheath keratinization.
46 citations
,
September 2007 in “Journal of Investigative Dermatology”
6 citations
,
November 2008 in “Hair transplant forum international” Using a special knife helps improve hairline scars from surgery.
4 citations
,
November 2016 in “The Journal of Dermatology” Pili torti hair is fragile due to loose keratin filaments and weak disulfide bonds.
August 2019 in “Journal of the American Academy of Dermatology” Older adults may experience painful finger pitting due to nerve changes in aging skin, and treatments can help reduce symptoms.
2 citations
,
May 2022 in “International journal of trichology” Plica neuropathica is a tangled hair condition that may be caused by hair damage or psychiatric issues and is treated by cutting the hair and addressing mental health.
6 citations
,
October 2006 in “International Journal of Dermatology” Hair splitting and nail detachment are linked conditions.
6 citations
,
January 2018 in “Dermato-endocrinology” Darkened knuckles can be an early sign of insulin resistance.
4 citations
,
April 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Krt16-deficient mice help understand skin disorders like PC and FNEPPK.
January 2023 in “Skin appendage disorders” Two Hispanic women developed Plica neuropathica, a condition causing tangled hair, possibly due to hair damage and various risk factors.
6 citations
,
September 2021 in “Experimental Brain Research” Rats have different touch receptors in their paws that help with movement and handling objects.
5 citations
,
January 2020 in “Skin Appendage Disorders” The nail strengthener with Pistacia lentiscus and hyaluronic acid improves brittle nails' appearance and strength.
January 2021 in “Skin Appendage Disorders”
September 2022 in “JAAD case reports” The man has a genetic skin condition called pachyonychia congenita.
24 citations
,
March 2008 in “Neuroscience Research” Cat paws have complex touch sensors for detailed sensory processing.
August 2024 in “Biomedical Journal of Scientific & Technical Research” A levered nail trimmer can improve comfort and wellness, especially for those with baldness.
6 citations
,
June 2024 in “Drug Testing and Analysis” Nails are being explored as an alternative to hair for evaluating long-term drug use, but differences in structure, growth, and drug incorporation between nails and hair can complicate analysis and interpretation. This review compiles literature comparing drug concentrations in hair, fingernails, and toenails, emphasizing studies with paired samples from the same individuals. While some drugs show clear results, more standardized studies are necessary to fully understand drug incorporation in nails and establish reliable cut-offs.
17 citations
,
April 1997 in “American Journal of Dermatopathology” PC-associated alopecia has unique microscopic features.
6 citations
,
May 2024 in “Developmental Biology”
13 citations
,
June 2010 in “Journal of The American Academy of Dermatology” A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.
36 citations
,
December 1991 in “Journal of Dermatological Science” Human nails contain both skin and hair keratins, each needing different extraction methods.
April 2025 in “Dermatology Practical & Conceptual” 4 citations
,
October 2015 in “JAAD Case Reports” Surgical grafting may fix nail issues caused by valproic acid.
15 citations
,
December 1972 in “Journal of Investigative Dermatology”
May 2015 in “Plastic and Reconstructive Surgery” A new method using bands and finger sheaths from gloves to manage hair during surgery is effective, quick, and reduces hair damage.
March 2012 in “Journal of The American Academy of Dermatology” Hand-foot-mouth disease may cause nail loss in children.
September 2023 in “Journal of the American Academy of Dermatology” Podiatrists perform nearly all nail excisions in the US.
61 citations
,
September 1994 in “Journal of Medical Genetics” Pachyonychia congenita is linked to a keratin gene on chromosome 17.
13 citations
,
April 2009 in “Journal der Deutschen Dermatologischen Gesellschaft” Nail disorders not caused by infection are common and can look similar, with psoriasis being the most frequent and having specific nail symptoms.