9 citations
,
October 2014 in “Experimental and Clinical Endocrinology & Diabetes” Knuckle Acanthosis Nigricans is common in Latin American youth and may indicate early insulin resistance, especially in those with normal weight.
88 citations
,
June 2000 in “Journal of Investigative Dermatology” Keratin 17 is important for hair and nail structure and affects pachyonychia congenita symptoms.
13 citations
,
January 2001 in “Pediatric dermatology” A dark-haired Chinese girl had hair that looked banded under certain light but was normal under a microscope.
10 citations
,
July 2001 in “PubMed” A new type of pachyonychia congenita may exist, caused by a different keratin mutation.
13 citations
,
October 2004 in “Anais Brasileiros De Dermatologia” The document concludes that compulsive hair disorders, like trichotillomania, are complex and require careful diagnosis and treatment from both psychiatric and dermatological perspectives.
June 2024 in “Annals of Medicine and Surgery” A 23-year-old Syrian woman has two rare hair disorders, and avoiding hair treatments plus using vitamins and minoxidil may help.
6 citations
,
November 2008 in “Hair transplant forum international” Using a special knife helps improve hairline scars from surgery.
14 citations
,
February 2007 in “The Journal of Bone and Joint Surgery” A baby's toe was saved from serious damage by quickly removing a hair wrapped tightly around it.
March 2026 in “Indian Journal of Dermatopathology and Diagnostic Dermatology” Corkscrew hairs can help diagnose trichotillomania.
July 2005 in “Journal of The American Academy of Dermatology” Using a cotton-tipped applicator as a base for cutting sutures helps make them a uniform length and reduces the risk of skin cuts.
119 citations
,
January 2000 in “British Journal of Dermatology” Different parts of the nail express different keratins, showing unique patterns of differentiation.
6 citations
,
October 2009 in “Veterinary Dermatology” Canine claws have complex structures with different keratin types, similar to hair and nails.
August 2021 in “Indian dermatology online journal” A young boy with a rare skin and nail condition improved significantly with simple topical treatments.
2 citations
,
June 2010 in “Medicina de Familia SEMERGEN” The girl's "dandruff" was actually harmless hair casts, not a hygiene issue.
Patients with graft-versus-host disease often have nail changes related to the nail matrix, with severity not linked to skin condition.
The study concludes that Twenty-nail dystrophy is more common in boys among children and in women among adults, with varying response to treatment.
6 citations
,
May 2024 in “Developmental Biology” 1 citations
,
December 2016 in “Revista română de medicină de laborator” The NIPAL4 mutation c.527C>A is common in Romanian patients with autosomal recessive congenital ichthyosis.
10 citations
,
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
2 citations
,
January 2007 in “Actas Dermo-Sifiliográficas” Two cases of hairy elbows syndrome were described, with normal skin texture and symmetrical hair growth.
Malnourished people have weaker hair that is easier to pluck.
2 citations
,
January 2025 in “Dermatology Practical & Conceptual” Nailfold dermoscopy is a simple, cheap way to check blood vessel changes in COVID-19 patients.
June 2025 in “British Journal of Dermatology” Consider amyloidosis in patients with specific nail changes and check for systemic issues.
The nail immune system is similar to hair but different from skin, with fewer immune markers.
January 2021 in “Nasza Dermatologia Online” Plica polonica is a rare condition where hair becomes irreversibly tangled, and the treatment is to cut the matted hair.
22 citations
,
November 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cystatin M/E helps in the final stages of hair and nail formation by controlling certain enzymes.
5 citations
,
June 2008 in “British Journal of Dermatology”
1 citations
,
October 2022 in “Dermatology practical & conceptual” Isolated patchy heterochromia with pili annulati can occur without other health issues.
17 citations
,
October 1981 in “American Journal of Clinical Nutrition” Malnourished people have weaker hair that is easier to pluck.