research Intracrine testosterone activation in human pancreatic β cells stimulates insulin secretion.
Testosterone in human pancreas cells boosts insulin production.
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research Medications affecting the insulin-like growth factor 1/growth hormone axis, including teprotumumab, somatostatin analogs, and anti-calcitonin gene-related peptide monoclonal antibodies, are associated with elevated reporting odds of alopecia in women: A pharmacovigilance study
Some drugs linked to growth hormones may increase the chance of hair loss in women.
research The Effects of Metformin, Ethinyl Estradiol/Cyproterone Acetate, and Metformin Ethinyl Estradiol/Cyproterone Acetate Combination Therapy on Carotid Artery Intima-media Thickness in Patients with Polycystic Ovary Syndrome
Metformin improves early signs of heart disease in women with PCOS and raises apelin levels, but doesn't significantly change artery thickness.
research Appropriate use of metformin in early pregnancy: is there a role for first trimester use?
Metformin is safe in early pregnancy for women with PCOS and may reduce certain risks.
research Drug Therapy in Polycystic Ovarian Syndrome
Low-dose flutamide-metformin therapy effectively improved PCOS symptoms in adolescent girls.
research Impaired Prolactin-Lowering Effects of Metformin in Women with Polycystic Ovary Syndrome
Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.
research A functional study of a case of glucagonoma exhibiting typical glucagonoma syndrome
A pancreatic tumor caused high glucagon levels and symptoms, but treatment reduced glucagon and shrank liver tumors.
research Effects of Glucagon-like Peptide-1 Receptor Agonists on Skin Homeostasis and Skin Aging Processes
GLP-1 RAs may help wound healing but can also cause faster facial aging and skin issues.
research G4, is a new transgenic mouse model for the polycystic ovaries syndrome
Researchers created a new mouse model, G4, that mimics human PCOS symptoms and links the condition to a specific gene.
research Il trattamento con metformina e clomifene citrato nelle donne con sindrome dell’ovaio policistico e infertilità
Metformin and clomiphene citrate together improve pregnancy chances and reduce miscarriages in women with PCOS.
research Enzalutamide/finasteride/goserelin/zoledronic-acid
research Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin
Mice skin has components that could help with hair growth and might be used for diabetes treatment.
research Pituitary Effects of Metformin in Men With Early‐Onset Androgenic Alopecia
Metformin reduces certain hormone levels in men with early-onset hair loss.
research A randomized controlled trial comparing total glucosides of paeony capsule and compound glycyrrhizin tablet for alopecia areata
Both treatments for alopecia areata are equally effective and safe.
research Rapid hair depigmentation in patient treated with pazopanib
Pazopanib treatment caused rapid hair color loss, possibly indicating its effectiveness.
research Intracrine testosterone activation in human pancreatic β cells stimulates insulin secretion.
Testosterone in our bodies helps increase insulin secretion from the pancreas.
research Use of metformin in pediatric age
Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.
research 53028 Semaglutide and Hair Loss: A Real-World Analysis
Semaglutide does not significantly increase the risk of hair loss.
research Effect of Metformin and Myo-inositol in Patients with Polycystic Ovary Syndrome
Combining metformin with myo-inositol is more effective for treating PCOS than metformin alone.
research Effects of calcitriol combined with metformin in the treatment of polycystic ovary syndrome and its influence on serum monocyte chemotactic factor -1
Calcitriol and metformin together are more effective for treating PCOS and lowering MCP-1 than metformin alone.
research Benefit-Risk Assessment of GLP-1 Receptor Agonists: Implications for Dermatologists and Plastic Surgeons
GLP-1 RAs help with diabetes and skin issues but can cause skin reactions and surgery challenges.
research Maternal obesity and the metabolic syndrome in reproductive health: assessing incretin-based interventions
The review addresses the impact of the global obesity epidemic on reproductive health, emphasizing the need for effective weight loss interventions during gestation to improve maternal and fetal health outcomes. It explores surgical and pharmacological strategies, with a focus on incretin-based therapies like GLP-1 receptor agonists and GIP dual agonists, which may enhance reproductive function and adapt to metabolic changes in pregnancy. These changes involve insulin signaling, lipid metabolism, and inflammatory regulation. The review also highlights the long-term risks of maternal obesity, such as increased likelihood of childhood obesity, underscoring the importance of managing gestational weight gain.
research Ameliorative Impact of High Inositol Diet on the Insulin Resistance and Metabolite Hormones among Women with Polycystic Ovary Syndrome
Eating a high inositol diet significantly improves insulin resistance and hormone levels in women with PCOS.
research EX VIVO DRUG SENSITIVITY EVALUATION OF A RARE ZMYM2::FGFR1+ LEUKEMIA PATIENT
Pemigatinib may be effective for treating ZMYM2::FGFR1 fusion-positive leukemia.
research Phase 2, double-blind, randomized, placebo-controlled study of the safety and efficacy of elagolix in women with polycystic ovary syndrome
Elagolix did not effectively treat polycystic ovary syndrome.
research Use of Glucagon-Like Peptide-1 (GLP-1) Agonists in Modulating Preexisting Dermatologic Disease: A Systematic Review
GLP-1 agonists may help treat certain skin conditions.
research The role of metformin in the management of polycystic ovary syndrome
Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.
research Affect of a six months treatment regiment of metformin (MET) on 17-hydroxyprogesterone (17P) responses to GnRH agonist (GnRH Ag) in polycystic ovary syndrome (PCOS)
Metformin can start ovulation and may lower 17P response in PCOS, but six months is too short to improve hair growth or change body fat distribution.
research Novel recombinant human acid α-glucosidase with optimal glycosylation is significantly better than standard of care enzyme replacement for glycogen clearance in skeletal muscles of GAA knock-out mice
research Metabolic and hormonal effects of a combined Myo-inositol and d-chiro-inositol therapy on patients with polycystic ovary syndrome (PCOS)
The combined Myo-inositol and D-chiro-inositol treatment improved weight, hormone levels, and skin conditions in women with PCOS.