research Polycystic ovary syndrome - Metformin treatment in pregnancy
Metformin reduces pregnancy complications in women with PCOS.
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510-540 / 1000+ resultsresearch Impaired metabolic effects of metformin in men with early-onset androgenic alopecia
Metformin is less effective in men with early-onset hair loss.
research Androstanediolglucuronide: A parameter for peripheral androgen activity before and during therapy with cyproterone acetate
3α-AdiolG is a good marker for androgen activity in women with excessive hair growth and decreases with anti-androgen treatment.
research Exploring the therapeutic potential of metformin in polycystic ovary syndrome: focusing on hyperandrogenism in a sample of Iraqi women
Metformin reduces high male hormone levels in women with PCOS.
research Metformin potential in predisposing arthralgia, type II cross reactivity secondary to group A streptococcus infection & other comorbidities in treating PCOS
Metformin can effectively treat PCOS but may cause serious side effects like joint pain and allergic reactions.
research GSK-3 Inhibitors: Recent Developments and Therapeutic Potential
Drugs that block GSK-3 show promise for treating various diseases.
research Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome
Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
research Effectiveness of Low-dose Ethinylestradiol/Cyproterone Acetate and Ethinylestradiol/Desogestrel with and without Metformin on Hirsutism in Polycystic Ovary Syndrome: A Randomized, Double-blind, Triple-dummy Study.
Both oral contraceptives reduced hirsutism in PCOS patients, but adding metformin showed no extra benefit.
research Ghrelin levels are suppressed and show a blunted response to oral glucose in women with polycystic ovary syndrome.
Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.
research Allopregnanolone promotes proliferation and differential gene expression in human glioblastoma cells
Allopregnanolone increases growth and changes gene activity in human brain cancer cells.
research Author reply
Imatinib mesylate can cause skin lightening, especially in Chinese patients, due to its effect on pigment production.
research Anti-hyperglycaemic and selected organ protective effects of Ziziphus spina-christi hydroethanol leaf extract in alloxan induced diabetic rats
Ziziphus spina-christi leaf extract lowered blood sugar and protected organs in diabetic rats.
research Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process
Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
research The Application of the Insulin to C-Peptide Molar Ratio (ICPR) in Primary Screening for Insulin Antibodies in Type 2 Diabetes Mellitus Patients: A Further Quantitative Study on the Relationship Between ICPR and Insulin Antibodies
2h-ICPR can help screen for insulin antibodies in type 2 diabetes patients.
research Lipin 1 Gene Polymorphisms in Polycystic Ovary Syndrome
Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.
research The curative effect of metformin in combination with dyne-35 on the treatment of polycystic ovary syndrome and on the ovulation rate and pregnancy rate
Metformin combined with dyne-35 increases ovulation and pregnancy rates in PCOS patients.
research ROLE OF METFORMIN AND VITAMIN D3 IN OBESE PCOS PATIENTS
Metformin and vitamin D3 help manage insulin resistance and hormonal imbalances in obese PCOS patients.
research Pharmacological management of polycystic ovary syndrome
PCOS treatment should be personalized, using birth control pills or metformin for symptoms, with lifestyle changes being essential.
research Pharmacological Approaches to Controlling Cardiometabolic Risk in Women with PCOS
Treatments for PCOS aim to reduce androgen levels and improve insulin sensitivity to lower cardiometabolic risk.
research The presence of insulin resistance and comparison of various insulin sensivity indices in women with androgenetic alopecia.
Women with androgenetic alopecia (AGA) are more insulin resistant than healthy women, with various insulin sensitivity indices being higher in the AGA group. An oral glucose tolerance test is suggested for women with AGA.
research The effect of metformin on hirsutism in polycystic ovary syndrome
Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.
research Self-assembling peptide inspired by insulin and type 1 insulin-like growth factor for the treatment of androgenetic alopecia
Ac-GFFY-IGF peptide is a promising, safe, and effective treatment for hair loss, better than current options.
research Glucose-Activated Nanoreactor Initiating Cascade Reaction to Remodel Immune Microenvironment for Promoting Diabetic Wound Healing
MCP@G improves diabetic wound healing by reducing stress and promoting tissue repair.
research Metformin treatment of polycystic ovary syndrome improves health-related quality-of-life, emotional distress and sexuality
Metformin improves quality of life, emotional health, and sex life in women with polycystic ovary syndrome.
research Intracrine Testosterone Activation in Human Pancreatic β-Cells Stimulates Insulin Secretion
Testosterone helps human pancreatic cells increase insulin release.
research Acarbose for Polycystic Ovary Syndrome
Acarbose may improve PCOS symptoms and fertility, but more research is needed.
research Sacituzumab Govitecan-Hziy (Trodelvy™)
Trodelvy™ helped some patients with advanced breast cancer, but had side effects.
research Polycystic Ovarian Syndrome
Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
research The metabolically protective energy expenditure increase ofPik3r1-related insulin resistance is not explained by Ucp1-mediated thermogenesis
Increased energy use in Pik3r1-related insulin resistance isn't due to Ucp1 thermogenesis.
research Sequential estrogen-progestin addition to gonadotropin-releasing hormone agonist suppression for the chronic treatment of ovarian hyperandrogenism: a pilot study.
The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.