6 citations
,
March 2003 in “Archiv Der Pharmazie” Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.
5 citations
,
August 2024 in “Skin Research and Technology” KLB and EIF3C genes are key for early diagnosis of vitiligo and alopecia areata.
2 citations
,
August 2019 in “PubMed” A specific enzyme that activates the hair growth medication minoxidil when applied to the skin was identified.
402 citations
,
August 2011 in “Cancer research” Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
2 citations
,
December 2023 in “Stem Cells Translational Medicine” ISX-9 helps stem cells heal lung injury better by boosting growth factor secretion.
March 2025 in “Journal of Endocrinology and Metabolism” Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.
23 citations
,
November 2015 in “Phytotherapy Research” Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.
March 2023 in “Scholars international journal of obstetrics and gynecology” PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.
September 2025 in “Experimental & Molecular Medicine” Small molecules KY19382 and KY19334 may help treat skin cancer by reducing CDK1 levels and blocking harmful cell signals.
8 citations
,
March 2004 in “Mammalian genome” KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
21 citations
,
April 2014 in “PLoS ONE” A rare gene variant causes hair and nail issues in a family.
13 citations
,
January 2017 in “Molecules” Compounds from Alpinia zerumbet may help with hair regrowth and cancer treatment by targeting PAK1.
22 citations
,
September 2003 in “Journal of Investigative Dermatology” New mutations in the EBP gene cause CDPX2, affecting bones, skin, eyes, and hair, with females generally less affected than males.
September 2025 in “Journal of the American Academy of Dermatology” Ritlecitinib may help treat alopecia areata by protecting hair follicles.
17 citations
,
June 2023 in “Pharmaceuticals” Inflammasome proteins may help diagnose and treat Parkinson's disease.
Mutations in specific genes cause different types of ectodermal dysplasias.
June 2025 in “Rapid Communications in Mass Spectrometry” The new method improves protein extraction and analysis in hair, aiding biomedical and forensic work.
Activating certain potassium channels in honey bees can lower antioxidant levels and reduce death rates during heavy mite infestations, potentially aiding their immune response.
January 2025 in “Dermatology Research and Practice” Higher activity in lichen planopilaris is linked to certain immune and tissue genes.
October 2023 in “The Egyptian Journal of Hospital Medicine ” PSA might help diagnose PCOS and related skin issues, but more research is needed.
3 citations
,
June 2025 in “Drug Design Development and Therapy” Targeting glycolysis may help treat PCOS by improving insulin sensitivity and ovarian function.
June 2024 in “Research Square (Research Square)” Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
22 citations
,
September 2024 in “Human Reproduction Update” Androgen measurement helps diagnose PCOS, but accuracy varies, needing standard methods.
73 citations
,
April 2006 in “BioTechniques” Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.
Different androgen concentrations affect wool-related gene expression differently in Hetian and Karakul sheep breeds.
April 2023 in “Journal of Investigative Dermatology” The research found that a protein called caveolin-1 is reduced in psoriasis, but reintroducing it can help alleviate some psoriasis symptoms.
Young women in Karachi have low awareness of PCOS and its risks, needing more education.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
July 2024 in “Journal of Investigative Dermatology” A KLK5 inhibitor effectively improved skin symptoms in a mouse model of Netherton Syndrome.
9 citations
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July 2016 in “Genes” Genetic variants in PDE6H and LPAR6 cause vision impairment and hair loss in two Pakistani brothers.