research Systematic Review of Platelet-Rich Plasma in Medical and Surgical Specialties: Quality, Evaluation, Evidence, and Enforcement
PRP shows promise but lacks consistent evidence and regulation.
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research Oral delivery of marine shellfish supramolecule peptides for skin wound healing
Eating peptides from certain shellfish may help wounds heal faster by reducing inflammation.
research Número de plaquetas e níveis de fatores de crescimento no plasma rico em plaquetas (PRP) fresco e liofilizado, e sua correlação com parâmetros de crescimento capilar e efeito clínico na alopecia androgenética = Platelet number and growth factors levels in fresh and lyophilized platelet rich plasma (PRP) and its correlation with hair growth parameters and clinical effect in androgenetic alopecia
research Toll-like Receptor 3 Agonist, Polyinosinic-polycytidylic Acid, Upregulates Carbonic Anhydrase II in Human Keratinocytes
A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.
research Platelet-Rich Plasma for Knee Osteoarthritis: A Comprehensive Narrative Review of the Mechanisms, Preparation Protocols, and Clinical Evidence
PRP is a promising and safe treatment for early to moderate knee osteoarthritis but needs standardized protocols.
research Loss of adipocyte phospholipase gene PLAAT3 causes lipodystrophy and insulin resistance due to inactivated arachidonic acid-mediated PPARγ signaling
Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.
research A Study on the effectiveness of autologous platelet-rich plasma gel in the treatment of chronic leg wounds.
research Platelet-rich plasma (PRP): history of the platelets� concentrates and current applications in medicine
PRP helps heal and repair tissues in medicine but needs more research for better use.
research Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes
Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.
research How to explain the beneficial effects of platelet‐rich plasma
Platelet-rich plasma may help healing due to growth factors from platelets.
research Platelet-Rich Plasma for Degenerative Spine Disease: A Brief Overview
PRP shows promise for spinal pain but needs more guidelines before widespread use.
research All Subcomponents of the Cutaneous Lupus Erythematosus Disease Area and Severity Index–Activity (CLASI-A) are Relevant to Identify and Detect Changes in Skin Activity
All parts of the CLASI-A score are important for assessing skin activity in cutaneous lupus erythematosus.
research Enhancing Burn Wound Healing with Autologous Platelet-Rich Plasma (APRP): A Promising Adjunctive Therapy
Platelet-rich plasma speeds up burn healing.
research 527 PTEN is a master driver of healing inhibition in venous leg ulcers by targeting immune response, angiogenesis and lymphangiogenesis
Targeting PTEN can improve healing in venous leg ulcers.
research The Combination of Stromal Vascular Fraction Cells and Platelet-Rich Plasma Mediates the Inflammatory Process in Deep Dermal Burn Injury.
Combining PRP and SVF speeds up burn healing by controlling inflammation.
research Silicone elastomer gel impregnated with 20(S)-protopanaxadiol-loaded nanostructured lipid carriers for ordered diabetic ulcer recovery
research Multimodal roles of transient receptor potential channel activation in inducing pathological tissue scarification
Targeting TRP channels may help reduce excessive scarring.
research Clinical and analytical evaluation of LC-MS methods for plasma renin activity and aldosterone
The study developed methods to measure biomarkers in mice and found differences in hormone levels linked to gut microbiota diversity and stress response.
research Effect of decellularisation methods on methacryloyl-substituted placental ECM hydrogels
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
research 466 Clinical technique and outcomes of platelet-rich plasma application for treatment of androgenic and scarring alopecia, acne scarring, melasma, and facial rejuvenation: A prospective multicenter study
Platelet-rich plasma treatment is generally safe and effective for hair loss, acne scars, skin discoloration, and facial rejuvenation, but deeper injections are better and multiple treatments can increase risk of side effects.
research Influence of prostaglandin F2α and its analogues on hair regrowth and follicular melanogenesis in a murine model
Prostaglandin F2alpha and related compounds can increase hair growth and darken hair in mice.
research Two-ligand priming mechanism for potentiated phosphoinositide synthesis is an evolutionarily conserved feature of Sec14-like phosphatidylinositol and phosphatidylcholine exchange proteins
A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.
research Pantolactams as androgen receptor antagonists for the topical suppression of sebum production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting
P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
research Phospholipase C 1 is required for skin stem cell lineage commitment
Phospholipase Cδ1 is crucial for normal skin and hair development.
research A histological Study of the Possible Therapeutic Effect of Platelet Rich Plasma on the Healing of Second Degree Skin Burn and Prevention of Scar Formation in Adult Male Albino Rat
Platelet-rich plasma helps heal second-degree burns and reduces scarring.
research Implication of allopregnanolone in the antinociceptive effect of N -palmitoylethanolamide in acute or persistent pain
PEA reduces pain by increasing neurosteroid synthesis in the spinal cord.
research LB793 A phase 1, open-Label, single ascending dose study in healthy subjects of the safety, tolerability and pharmacokinetics of ASLAN004, a novel IgG anti-IL-13 receptor alpha 1 Inhibitor
ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.
research Autolougous platelet concentrates in esthetic medicine
Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.
research The Additive Effect of Platelet-Rich Plasma in the Treatment of Actively Bleeding Peptic Ulcer
Platelet-rich plasma treatment is more effective and cost-efficient than epinephrine for healing bleeding peptic ulcers, with fewer complications and rebleeding cases.