77 citations
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July 2020 in “Journal of the European Academy of Dermatology and Venereology” Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
77 citations
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April 1999 in “Dermatologic Clinics” The document concludes that follicular unit transplantation offers more natural results and better graft survival than older hair transplant methods.
66 citations
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July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
59 citations
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May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
54 citations
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August 2009 in “Dermatologic Surgery” Modern hair transplants use small grafts for a natural look and drugs to prevent further loss, with high patient satisfaction.
52 citations
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September 2018 in “International Journal of Molecular Sciences” Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.
52 citations
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October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
51 citations
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January 2024 in “Nanoscale” Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
46 citations
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March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
46 citations
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July 1988 in “Journal of The American Academy of Dermatology” Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
45 citations
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January 2020 in “Pharmaceutical Biology” Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.
32 citations
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December 2014 in “Journal of experimental botany” Certain proteins are essential for the growth of root hairs in barley.
32 citations
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December 2000 in “Phytomedicine” Apple-derived procyanidin B-2 can safely promote hair growth in men.
31 citations
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January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
31 citations
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September 2016 in “PLoS ONE” Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
29 citations
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September 2012 in “Birth Defects Research” Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
27 citations
,
November 2008 in “Facial Plastic Surgery” Follicular Unit Extraction is a less invasive hair transplant method with potential for natural results but has challenges like longer surgery time and higher cost.
25 citations
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November 2018 in “Cell reports” The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
24 citations
,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
22 citations
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May 2021 in “Nature Communications” Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
22 citations
,
October 2012 in “Cell Transplantation” Cells treated with Wnt-10b can grow hair after being transplanted into mice.
21 citations
,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
19 citations
,
January 2013 in “International journal of medical sciences” Increasing Wnt5a in mice skin delays hair growth but doesn't stop it.
18 citations
,
December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
18 citations
,
November 2014 in “Journal of Agricultural and Food Chemistry” Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.
16 citations
,
September 2018 in “Journal of Ethnopharmacology” Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
16 citations
,
December 2006 in “International Journal of Dermatology” A woman died from cancer that spread from a long-standing cyst on her abdomen.
16 citations
,
January 2006 in “The Aging Male” Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
15 citations
,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.
14 citations
,
April 2019 in “Saudi pharmaceutical journal” Microparticles help caffeic acid stay longer in hair follicles for better treatment of folliculitis.