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A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.

The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.

Itraconazole-loaded nanoparticles are more effective and less toxic for treating fungal infections than conventional oral itraconazole.

Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.

Complex basal cell carcinomas need personalized treatment due to unique genetic mutations.

New steroid derivatives show promise as anticancer agents, even against resistant cells.

PXX is an effective and affordable photocatalyst for creating new chemical bonds in organic synthesis.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Nails could be used to check long-term drug use, but more research is needed.

Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.

Thallium is highly toxic, causing severe health issues, and Prussian blue is the best antidote.

The bio-based complex effectively repairs and protects chemically damaged hair.

Raltitrexed conjugates are less potent than the free drug but more effective at high concentrations.

PROTACs show promise for cancer treatment, but designing them effectively is challenging.

Understanding how keratin structures in hair are arranged and interact is key for creating methods to extract and purify them.

The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.

Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.

Keratin from hair binds well to gold and BMP-2, useful for bone repair.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

PCOS causes hormonal imbalances and health issues like infertility and heart disease.

Adding a second method to PROTACs could improve cancer treatment.

Heavy metals can damage skin and hair in mice.

The research linked PLCD1 gene variants to the development of trichilemmal cysts.

CoCr2O4 catalysts effectively and sustainably produce diaminopyrimidine oxides with high yield.

BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.