research First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours.
ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.
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research Polycystic ovary syndrome and estroprogestins
Choosing the right estroprogestin is crucial for effectively managing PCOS symptoms.
research First-line therapy with gemcitabine and paclitaxel in locally, recurrent or metastatic breast cancer: A phase II study
Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
research Prevalence of Demodex spp. in students and employees of the Pomeranian Medical University in Szczecin
Demodex mites were more common in older personnel than students, especially in eyelashes.
research Doxetaxel: new indication. Prostate cancer: a few more weeks.
Docetaxel slightly extends prostate cancer survival but has significant side effects and high cost.
research Technical Advancement and Biomedical Application of Multiphoton Excitation Microscopy
Multiphoton excitation microscopy is a promising tool for deep tissue imaging and clinical applications.
research Limits of Visual Detection for Finasteride Polymorphs in Prepared Binary Mixtures: Analysis by X‐ray Powder Diffraction
research CURRENT PROSPECTIVE IN THE MANAGEMENT OF DEPRESSION USING OFF LABELLED DRUGS AND ADVANCED DRUGS
New medications are improving depression treatment, emphasizing accurate diagnosis and chronic care.
research Digital measurement of melasma: Towards eliminating subjectivity from treatment evaluation
The digital system for measuring melasma shows promise but needs more development for better accuracy and automation.
research Quality of life case series review: wound bed preparation from a UK perspective
PHMB products improve wound healing and quality of life.
research Aqueous Extract of Bacopa procumbens and the NAPEL Formulation Mitigate MPTP-Induced Neurotoxicity via Nrf2/HSF1/HIF-1α Signaling in a Parkinson’s Disease Model
Bacopa procumbens extract may help protect the brain in Parkinson's disease.
research Tunable Structured Metal Oxides for Biocatalytic Therapeutics
Tunable structured metal oxides show promise for various medical treatments due to their versatility and cost-effectiveness.
research SATU KASUS ALOPESIA ANDROGENIK YANG DITERAPI <i>MICRONEEDLING PLATELET-RICH </i>PLASMA
Microneedling with PRP effectively improved hair growth and thickness in androgenic alopecia without side effects.
research <p>Telogen effluvium: a comprehensive review</p>
The document concludes that Telogen Effluvium is a hair loss disorder that can be assessed with the modified wash test and may be treated with clobetasol foam, with patient management being important.
research Meibomian Gland Dysfunction: Intense Pulsed Light Therapy in Combination with Low-Level Light Therapy as Rescue Treatment
Combined light therapy improves eye health and quality of life for those with meibomian gland dysfunction.
research Ectrodactyly, Ectodermal Dysplasia, and Cleft Lip/Palate Syndrome with Concomitant Lymphopenia: A Novel TP63 Mutation
A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.
research Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models
Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.
research Changes in Prolactin and Insulin Resistance in PCOS Patients Undergoing Metformin Treatment: A Retrospective Study
Lower baseline prolactin levels may lead to better insulin resistance improvement with metformin in PCOS patients.
research 43237 Infantile Perianal Pyramidal Protrusion (IPPP): A Retrospective Review of 28 Patients
Recognizing IPPP is crucial to prevent misdiagnosis and unnecessary treatments.
research The post-finasteride syndrome: possible etiological mechanisms and symptoms
Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.
research U.K. Psychodermatology Society Annual Meeting, St Thomas’ Hospital, London, 25 January 2018
I'm sorry, but I can't provide a summary as no specific conclusion or information from the meeting is provided.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens against E2F1-Driven Melanoma Progression
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
research Epimedium brevicornum Maxim. Extract exhibits pigmentation by melanin biosynthesis and melanosome biogenesis/transfer
Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.
research A case of sarcoidal foreign body reaction to permanent makeup: the involvement of M2 macrophages
Steroid injections improved symptoms and hair regrowth in a woman with a reaction to permanent makeup.
research Prescription Appropriateness of Cyproterone Acetate/Ethinylestradiol in Primary Care: A Population-Based Study in Italy
The study found that prescribing patterns for Cyproterone Acetate/Ethinylestradiol in Italy did not significantly change after EMA recommendations.
research Inverse micellar sugar glass (IMSG) nanoparticles for transfollicular vaccination
IMSG nanoparticles improve vaccine delivery and immune response through hair follicles.
research Computer-Aided Designing Peptide Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase Combined Molecular Docking and Molecular Dynamics Simulation
Two peptides, RMYYY and VMYMI, may be effective anti-inflammatory drugs.
research Oestrogen receptor evaluation in Pomeranian dogs with hair cycle arrest (alopecia X) on melatonin supplementation
Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.
research Faster calculation of scalp area in androgenetic alopecia before platelet-rich plasma therapy using the mobile application ImageMeter
Mobile app ImageMeter calculates scalp area faster and reliably for alopecia treatment.
research Clinical effectiveness of ethinylestradiol-cyproterone acetate and raloxifene combination therapy in polycystic ovary syndrome-associated infertility
The combination therapy effectively treats infertility in PCOS without major side effects.