101 citations
,
May 2014 in “PLOS ONE” Women with PCOS have a higher chance of experiencing depression, anxiety, and sleep disorders.
100 citations
,
June 2002 in “Diabetologia” Parents of women with PCOS have a higher risk of Type II diabetes and insulin resistance, especially fathers.
99 citations
,
August 2003 in “Fertility and Sterility” Too much male hormone is the main cause of Polycystic Ovary Syndrome.
98 citations
,
May 2020 in “Journal of Functional Morphology and Kinesiology” Exercise, especially vigorous aerobic and resistance training, can improve hormone levels in women with PCOS.
97 citations
,
July 2006 in “Dermatologic therapy” The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.
96 citations
,
February 2007 in “The Journal of Clinical Endocrinology & Metabolism” Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.
96 citations
,
October 1987 in “The Journal of Clinical Endocrinology & Metabolism” Chronic GnRHa treatment can help manage endometrial hyperplasia and reduce ovarian androgen excess in PCO patients.
92 citations
,
May 2014 in “The American Journal of Medicine” The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.
91 citations
,
April 2017 in “Diabetes & Metabolic Syndrome: Clinical Research and Reviews” Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.
91 citations
,
November 2007 in “European journal of endocrinology” Metformin helps with PCOS symptoms no matter the patient's initial insulin resistance or weight.
90 citations
,
January 2021 in “Clinical Endocrinology” Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.
90 citations
,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.
90 citations
,
July 2009 in “PTR. Phytotherapy research/Phytotherapy research” Spearmint tea may reduce testosterone and self-reported hair growth in women with PCOS.
90 citations
,
August 2002 in “European journal of endocrinology” Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.
89 citations
,
November 2014 in “Medical Clinics of North America” Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
84 citations
,
November 2003 in “European journal of endocrinology” Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.
81 citations
,
May 2019 in “Frontiers in Endocrinology” Melatonin may improve some hormonal and inflammatory issues in women with PCOS.
77 citations
,
March 2004 in “Human Reproduction” Women with irregular periods and/or excessive body hair are more likely to have polycystic ovaries, and this condition is linked to higher health risks.
75 citations
,
July 2013 in “The Journal of Clinical Endocrinology and Metabolism” Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
74 citations
,
January 2006 in “Endocrine journal” Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.
73 citations
,
June 2008 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.
73 citations
,
February 2007 in “The American Journal of Medicine” PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.
71 citations
,
July 2015 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.
70 citations
,
February 2025 in “Journal of Ovarian Research” PCOS involves hormonal imbalance, cysts, and ovulation issues, affecting health and increasing disease risks.
70 citations
,
April 2013 in “Endocrine” Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.
69 citations
,
November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
69 citations
,
September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
68 citations
,
January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
67 citations
,
February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
66 citations
,
November 2001 in “European journal of endocrinology” Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.