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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Some people have a genetic variation that makes them less effective at breaking down drugs.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Targeted photodynamic therapy is a promising method for precise disease treatment and diagnosis.

Finasteride is mainly broken down by the enzyme CYP3A4, affecting its levels in the body.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

Taking vitamin B6 corrected a pregnant woman's metabolic disorder, which changed her hair color.

Lowering homocyst(e)ine levels can reverse skin and hair lightening by restoring enzyme activity needed for pigmentation.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Cystine is crucial for forming keratin in hair, wool, and nails.

Dermoscopy helped correctly diagnose a skin condition that was previously misidentified as a different hair loss disease.

Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.

Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.

Certain polyphenols may help treat skin pigmentation disorders.

Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Metabolic disorders can cause hair structure defects and growth issues, but amino acid levels in hair remain normal.

Iron is crucial for skin health, with specific proteins recycling it to support skin functions and prevent its release.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

Finasteride's metabolites were identified, helping understand how the drug is processed in the body.

Canine hair follicle cells convert progesterone into various metabolites, mainly cortisol.

Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.