16 citations
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April 1978 in “Genetics Research” Mice with the ab gene have abnormal sebaceous gland development, affecting sebum production.
15 citations
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December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
189 citations
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May 1999 in “Microscopy Research and Technique” Neurotrophins, especially NGF, are crucial for pain development and management.
67 citations
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August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
April 2023 in “Journal of Investigative Dermatology” The research mapped gene activity in developing mouse skin and found key markers for skin cell types and changes from fetal to early postnatal stages.
237 citations
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February 2016 in “Science Translational Medicine” The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
11 citations
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January 1992 in “PubMed” TGF-beta 1 and IGF-II mRNA have specific patterns in pig subcutaneous tissue, affecting fat and muscle development.
53 citations
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October 2003 in “Developmental Biology” Too much Sonic Hedgehog protein stops hair growth in embryos.
6 citations
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October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
2 citations
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June 2006 in “Experimental dermatology” Skin patterns form through molecular signals and genetic factors, affecting healing and dermatology.
15 citations
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January 1999 in “Reproduction Fertility and Development” Merino sheep have fewer wool follicles at birth than before birth.
11 citations
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March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
27 citations
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February 2020 in “EMBO Reports” MEX3A is crucial for maintaining intestinal stem cells in mice.
15 citations
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May 2003 in “The Laryngoscope” FGF-1 causes spiral ganglion neurites to branch more.
1 citations
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December 2018 in “Sovremennye tehnologii v medicine” Disruptions in Wnt signaling can lead to skin and hair diseases.
May 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Truncated LTBP-1 disrupts TGF-beta signaling, affecting hair growth.
September 2016 in “Journal of Dermatological Science” Protein extract from embryonic skin can create new hair follicles in adult life, primarily through effects on fibroblasts.
18 citations
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January 2013 in “Psychoneuroendocrinology” Neonatal neurosteroid levels affect adult brain function and behavior.
46 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
35 citations
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September 2009 in “Psychoneuroendocrinology” Early-life neurosteroid changes affect adolescent exploration and adult behavior.
15 citations
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January 2010 in “Experimental Dermatology” Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.
10 citations
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February 2007 in “Current Opinion in Endocrinology, Diabetes and Obesity” Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.
February 2024 in “Brain research bulletin” Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
1 citations
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October 2023 in “International Journal of Ayurvedic Medicine” Rasayana therapy can enhance female reproductive health at different life stages.
176 citations
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January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Early regulatory T cells are crucial for normal skin pigmentation.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
51 citations
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January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.