research Predictive Skin Permeation of Ethinylestradiol,α-Asarone,Finasteride and Risperidone
The Potts-Guy model best predicts skin permeability for the tested drugs.
Search
for
Sort by
Research
780-810 / 1000+ resultsresearch In-vitro permeation of drugs into porcine hair follicles: is it quantitatively equivalent to permeation into human hair follicles?
Porcine hair follicles can effectively model human hair follicles for drug absorption.
research Scanning Electrochemical Microscopy of Iontophoretic Transport in Hairless Mouse Skin. Analysis of the Relative Contributions of Diffusion, Migration, and Electroosmosis to Transport in Hair Follicles
Hair follicles significantly enhance electroosmotic transport during iontophoresis.
research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.
Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
research Stimulation of Cl conductance by minoxidil sulfate and K conductance by minoxidil in eccrine clear cells.
Minoxidil sulfate affects Cl channels, while minoxidil affects K channels in cells.
research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
research In Vitro, Ex Vivo, Penetration (EpiDermTM) and in Vivo Dermatokinetics of Ketoconazole Loaded Solid Lipid Nanoparticles for Topical Delivery
Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.
research Analysis of hair follicle penetration of lidocaine and fluorescein isothiocyanate-dextran 4 kDa using hair follicle-plugging method
Hair follicles are important for the absorption of certain drugs into the skin.
research Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process
Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
research Impact of Ester Promoieties on Transdermal Delivery of Ketorolac
Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research PEG-Immobilized Keratin for Protein Drug Sequestration and pH-Mediated Delivery
PEG and keratin scaffolds can effectively deliver protein drugs by controlling release based on pH levels.
research Effects of Nitrendipine (BAY e 5009), Nifedipine, Verapamil, Phentolamine, Papaverine, and Minoxidil on Contractions of Isolated Rabbit Aortic Smooth Muscle
Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
research Formulation and in vitro evaluation of polymeric enteric nanoparticles as dermal carriers with pH-dependent targeting potential
Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.
research Hair Biology
The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
research Petechiae on the fingertips as presenting symptom of dermatitis herpetiformis Duhring
Red spots on fingertips can be a sign of a skin condition linked to gluten sensitivity, treatable with a gluten-free diet.
research Minoxidil opens mitochondrial KATP channels and confers cardioprotection
Minoxidil protects heart and improves recovery.
research Determination of finasteride in human plasma by liquid–liquid extraction and high-performance liquid chromatography
Valid method measures finasteride in plasma, simple, fast, and affordable.
research Lack of effect of spironolactone on hair shaft diameter in hirsute females
Spironolactone did not make hair thinner in women with excess hair growth.
research Alopecia From Oral Contraceptives
Oral contraceptives may cause hair loss in women.
research The coudability sign of alopecia areata: the real story
The document concludes that anticonvulsants like phenytoin may cause skin reactions by affecting tryptophan metabolism and suggests researching vitamin levels in patients with drug reactions.
research Hair loss and its management in children
The document concludes that early diagnosis and a comprehensive treatment plan are crucial for managing hair loss in children, with a focus on both medical and psychological support.
research Tinea Capitis: Mixed or Consecutive Infection with White and Violet Strains of Trichophyton violaceum : A Diagnostic or Therapeutic Challenge
Treating a boy's scalp infection was challenging because two different colors of the same fungus appeared.
research A study on histopathological and dermoscopic correlations in pityriasis versicolor
Dermoscopic and histopathological features combined can help diagnose Pityriasis versicolor.
research Tea and Tea Product Diversification: A Review
Diversifying tea products can boost profits and meet global market demands.
research Black dot tinea capitis caused by trichophyton rubrum in an adult female presenting with cicatricial alopecia
A woman's scalp infection caused by a fungus led to permanent hair loss and was hard to treat but responded to a specific antifungal.
research Liquid Protein Diets and Telogen Effluvium: A Case Report
A liquid protein diet caused hair loss in a young woman.
research A report on the dissolved bioactive compounds of medicinal values in the high altitude hotsprings of Ladakh
Ladakh hotsprings contain compounds with potential medicinal benefits for various health conditions.
research Minoxidil suppressed cerebral ischemic injury by direct effect on neural tissues but not by reducing blood pressure.
Minoxidil protects brain tissue directly, not by lowering blood pressure.
research Nail and hair changes in chronic kidney disease patients
Nail and hair changes are common in severe chronic kidney disease and should be treated to improve patients' quality of life.