48 citations
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October 1996 in “Dermatologic clinics” Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.
45 citations
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January 2010 in “International journal of trichology” Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.
43 citations
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July 2016 in “European journal of pharmaceutical sciences” Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.
41 citations
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June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
41 citations
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November 2003 in “Annals of the New York Academy of Sciences” Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
40 citations
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April 2018 in “Endocrine” PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
38 citations
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January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
32 citations
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September 2018 in “Clinical Obstetrics and Gynecology” Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
32 citations
,
January 2012 in “International Journal of Dermatology” Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
30 citations
,
January 1997 in “Journal of Dermatological Treatment” Topical finasteride helps regrow hair and reduce balding without side effects.
29 citations
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July 2009 in “BJU international” Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
28 citations
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September 2013 in “Expert Opinion on Therapeutic Patents” New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
28 citations
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January 2010 in “Biological & pharmaceutical bulletin” Certain essential oils can activate a human skin receptor, potentially helping with skin disorders.
27 citations
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October 2001 in “Journal of Medicinal Chemistry” Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.
27 citations
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January 2001 in “Endocrine Practice” Finasteride cream reduces hair growth in women with hirsutism, but more research needed.
26 citations
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July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
25 citations
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August 2010 in “Acta Biomaterialia” Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
25 citations
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January 2005 in “Pediatric Dermatology” Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.
24 citations
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May 2016 in “Stem Cell Reviews and Reports” The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
24 citations
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May 1982 in “Biochemical Pharmacology” These drugs cause hair growth without affecting testosterone or adrenal hormones.
23 citations
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June 2017 in “Drug Design Development and Therapy” Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
23 citations
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January 2010 in “Journal of The American Academy of Dermatology” Effective treatments for lichen planopilaris are unclear due to inconsistent results and a lack of strong research evidence.
23 citations
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July 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
23 citations
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June 1950 in “American journal of diseases of children” Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.
22 citations
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October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
22 citations
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November 1998 in “Archives of Dermatology” Alternative medicine lacks scientific support and relies on the placebo effect, but remains popular and integrated into German healthcare.
21 citations
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January 2005 in “Pediatric Dermatology” An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
20 citations
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January 2018 in “Expert opinion on emerging drugs” JAK inhibitors may soon be a safe and effective treatment for alopecia areata.
20 citations
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February 1977 in “Circulation” Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.
19 citations
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October 2020 in “Biomedical Microdevices” Derma rollers show promise for skin improvement and drug delivery, but more research is needed on their safety and effectiveness.