research Case Report: PTCH1 splice-site mutation and sonidegib treatment in Gorlin-Goltz syndrome: clinical insights from a family case study
Personalized sonidegib dosing can effectively treat Gorlin-Goltz syndrome with fewer side effects.
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930-960 / 1000+ results research Faculty Opinions recommendation of Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation.
GLABRA2 represses root hair formation by inhibiting a specific gene.
research Investigation of ROP GTPase Activity and Cytoskeleton Dynamics During Tip Growth in Root Hairs and Pollen Tubes
ROP GTPase helps control the growth of pollen tubes and root hairs by managing cell structure and movement.
research Photobiomodulation in 3D tissue engineering
PBM helps improve cell survival in 3D tissue engineering.
research Research Snippets
New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.
research Androgenetic alopecia. Modelling progression and regrowth
AGA causes hair loss through follicle miniaturization and hair cycle changes; regrowth depends on anagen initiation in kenogen follicles.
research Aspect-Level Drug Reviews Sentiment Analysis Based on Double BiGRU and Knowledge Transfer
A model called PM-DBiGRU was developed for analyzing sentiments in drug reviews, and it performed better than other models, but struggled with complex sentences and situations requiring background knowledge.
research Generating mouse models of degenerative diseases using Cre/lox-mediated in vivo mosaic cell ablation
The study created a mouse model to mimic degenerative diseases for testing tissue repair and new therapies.
research Modeling cell–cell communication for immune systems across space and time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Association between PITX2 polymorphism and androgenetic alopecia in the Indian population
Certain gene variations in PITX2 are linked to a higher risk of male pattern baldness in Indians.
research Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways
Mathematical modeling helps understand and predict the MAPK cell signaling pathway.
research A Temporal Mathematical Model of Alopecia Areata: Investigating Hair Cycle Dynamics and Disease Progression
The model helps understand alopecia areata and suggests ways to improve treatment by targeting immune issues.
research Photo-responsive fibers as artificial hairs in an in-vitro model for transdermal drug delivery
Artificial hair fibers improve drug delivery accuracy through skin models.
research 561 Vellus-to-terminal hair follicle reconversion does occur in male pattern balding in a new humanized mouse model of androgenetic alopecia and is promoted by minoxidil and PRP
Minoxidil and PRP can help convert miniaturized hair follicles back to normal in male pattern baldness.
research Can an in vitro hair drug model be developed using dermal papilla cells alone?
Dermal papilla microtissues could be useful for initial hair growth drug testing.
research A Body Divided: Toward Reunification of the Paradigm
The body and mind should be seen as interconnected for better medical understanding and treatment.
research Incidence of alopecia in brain tumour patients treated with pencil scanning proton therapy and validation of existing NTCP models
A standardized scoring system is needed to improve model reliability for predicting hair loss in brain tumor patients treated with proton therapy.
research Assessment of the Ability of the ChatGPT-5 Model to Pass the Endocrinology Specialization Exam
ChatGPT-5 can pass the endocrinology exam but isn't fully reliable for clinical decisions yet.
research Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.
research Minimizing Factual Inconsistency and Hallucination in Large Language Models
A new method improves the accuracy and reliability of language models by up to 42%.
research Modeling the Psychiatric Aspects of Polycystic Ovary Syndrome and Induced Stress
Stress and PCOS together may increase depression and anxiety-like behaviors.
research TESTOSTERONE-INDUCED ANDROGENETIC ALOPECIA MICE MODEL: A PRELIMINARY STUDY
A testosterone-induced hair loss model in mice was successfully created for future research and treatment testing.
research Generalized Pustular Psoriasis
Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.
research Faculty Opinions recommendation of Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation.
GLABRA2 gene controls root-hair growth by regulating phospholipid signaling.
research The inheritance of common baldness: Two B or not two B ?
Common baldness is likely inherited through multiple genes, not just one.
research Making Waves with Hairs
Skin patterns are formed by simple reaction-diffusion mechanisms.
research 23 Hair and Nail Disorders
Hair and nail disorders can harm self-esteem, but early treatment helps.
research A syndromic extreme insulin resistance caused by biallelic POC1A mutations in exon 10
Mutations in the POC1A gene can cause a unique form of extreme insulin resistance and short stature.
research Generation of iPS-derived model cells for analyses of hair shaft differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research The Expression of P-Responsive Genes is Related to Root Hair Growth
Certain genes may promote longer root hairs in plants when phosphorus is low.