50 citations
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September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
50 citations
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October 1918 in “The journal of experimental zoology” Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.
47 citations
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July 1967 in “Science” Not eating enough protein can cause hair roots to shrink and lose color, and hair to become thinner.
45 citations
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July 2009 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
42 citations
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July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
42 citations
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April 2012 in “Seminars in Oncology” Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.
42 citations
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July 2007 in “Journal of Biological Chemistry” Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
41 citations
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September 2014 in “Journal of Pharmacy and Pharmacology” Melatonin may help treat PCOS symptoms in rats.
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September 1991 in “Medical hypotheses” Prolactin may be important for skin growth and immune function.
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June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” FA2H is essential for normal fur and sebum production in mice.
39 citations
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March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” GLI2 increases follistatin production in human skin cells.
39 citations
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January 1994 in “European Journal of Cancer” Scalp cooling is largely ineffective in preventing hair loss from breast cancer chemotherapy.
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June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
37 citations
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April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
36 citations
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September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
36 citations
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March 2002 in “Journal of Biological Chemistry” Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
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July 1977 in “The Journal of Pediatrics” Minoxidil helps lower blood pressure in kids with severe hypertension, but may cause temporary excessive hair growth.
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June 2005 in “The Milbank Quarterly” The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.
32 citations
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February 2017 in “Oncotarget” Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
30 citations
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February 2018 in “Journal of Pharmacy and Pharmacology” Hedychium spicatum has medicinal properties but needs more research for scientific validation and use.
30 citations
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December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
29 citations
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July 2010 in “Journal of Cutaneous Medicine and Surgery” Treatments for Frontal Fibrosing Alopecia have not been proven effective.
29 citations
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March 2008 in “Postcolonial Studies” The article concludes that the global hair trade is exploitative and reflects complex cultural and economic issues.
27 citations
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June 2013 in “Alcoholism: Clinical and Experimental Research” Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.
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May 1982 in “Biochemical Pharmacology” These drugs cause hair growth without affecting testosterone or adrenal hormones.
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December 2009 in “International Journal of Sport Management and Marketing” The document concludes that future research should focus on tailored solutions for managing sports crises and consider legal and cultural factors.
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May 1976 in “Archives of Dermatology” Stopping fluoride toothpaste use might improve perioral dermatitis.
20 citations
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June 2012 in “British Journal of Dermatology” Bleaching hair damages protein structure, especially keratin, leading to weakened hair.
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February 1977 in “Circulation” Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.
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December 2002 in “Journal of Liquid Chromatography & Related Technologies” New method quickly and accurately measures finasteride in tablets.