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20(S)-Protopanaxadiol-aglycone may help prevent and treat prostate cancer by reducing androgen receptor activity.

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

A cream with a specific hormone blocker increases hair growth in mice.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

Blocking mTORC1 reduces skin tumor growth in mice.

Epiprofin suppresses parathyroid hormone gene activity, helping regulate calcium levels and could be a treatment target for hyperparathyroidism.

GLP-1 receptor agonists can help manage PCOS metabolism but need careful use before conception.

Two new enzymes, PAD-R11 and PAD-R4, were cloned and showed activity, with PAD-R11 resembling epidermal enzymes.

AMPK activation may reduce melanoma risk in red-haired individuals.

The study found that p63 needs signals from morphogens to help skin cells differentiate properly.

Paxillin may help manage androgen-related disorders like PCOS by stabilizing androgen receptor proteins.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

Piperonylic acid may help hair growth and treat hair loss.

Lysophosphatidic acid boosts stem cell growth and movement by creating reactive oxygen species.

PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.

Androgen receptor inactivation delays skin cancer onset and reduces incidence in mice, with gender differences in susceptibility.

AP-2α and AP-2β are crucial for healthy skin and hair.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

AHR ligands could treat inflammatory skin diseases.