research Skin steroidogenesis in health and disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
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research Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Decreased lipin 1β expression in visceral adipose tissue is associated with insulin resistance in polycystic ovary syndrome
Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.
research The role of leptin in selected skin diseases
Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
research Progress and prospects: gene therapy for performance and appearance enhancement
Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.
research Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle
Cholesterol transport in hair follicles decreases from growth to regression phase.
research Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells
Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
research The seasonal development dynamics of the yak hair cycle transcriptome
Yak hair growth is influenced by genes and hormones, helping them adapt to alpine environments.
research Can the Second to Fourth Digit Ratio (2D : 4D) Be a Marker to Determine Ankylosing Spondylitis Disease Activity?
The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.
research LB1077 Cutaneous responses to systemic iron: A potential role for epidermal turnover in mammalian iron excretion
Skin may help in getting rid of excess iron through the process of skin cell renewal.
research LB1076 Using the frog embryonic epidermis as a model to study desmosome function during development
Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
research Utjecaj prehrane i dodataka prehrani na acne vulgaris
Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.
research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions
BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
research Genetic Variants Associated with Hyperandrogenemia in PCOS Pathophysiology
Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
research The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research Retinoids Putting the “A” in Alopecia
Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.
research Resident Stem Cell in Skin
Skin stem cells can help improve skin repair and regeneration.
research 440 Topical application of anti-cancer drug Bortezomib stimulates proliferation of follicular cells and induces expression of hair keratins via GATA-3 transcription factor
Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.
research 441 RPGRIP1L facilitates desmosomal adhesion through suppressing PKCβII-mediated desmoglein endocytosis: Implication in pemphigus
RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.
research Wound Healing and the Use of Medicinal Plants
Some medicinal plants can help heal wounds and may lead to new treatments.
research Treatment of frontal fibrosing alopecia and lichen planopilaris: a systematic review
No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
research Beyond acne: Current aspects of sebaceous gland biology and function
The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
research Clinical and biological impact of the exposome on the skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research Alternative treatment of polycystic ovary syndrome: pre-clinical and clinical basis for using plant-based drugs
Plant-based drugs are effective and safe alternatives for managing PCOS symptoms.
research Resveratrol derivatives: a patent review (2009 – 2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Hair and scalp disorders in women of African descent: an overview
The document concludes that clinicians should be aware of common hair and scalp disorders in women of African descent and that more research is needed to develop effective treatments.
research Are hair follicle stem cells promising candidates for wound healing?
Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.