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research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder
Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
research The Wonder Tool Platelet Rich Plasma in Cosmetic Dermatology, Trichology and Hair Transplant
PRP therapy is effective for hair regrowth and improving hair quality with minimal side effects.
research Plant elicitor Peptides regulate root hair development in Arabidopsis
Peps help Arabidopsis plants grow more root hairs by affecting specific genes and calcium signaling.
research Pinkie, the First Viable Germline Hypomorph Allele of Retinoid X Receptor Alpha, Reveals an Important Role for RXRa in Th2 Development.
RXRa is crucial for Th2 immune cell development and may link nutrition to immune health.
research Effect of intra-articular Platelet Rich Plasma injection on knee Osteoarthritis patients
PRP injections can effectively improve knee osteoarthritis symptoms.
research Correspondence
RAPK is a rare skin disorder with pigmented spots, mainly on hands and feet, starting in youth.
research Pigmented Rings With Central Clearing: A Dermoscopic Feature of Melasma
Pigmented rings with central clearing help diagnose melasma more accurately.
research Platelet-rich plasma as a site-targeted approach in wound healing: a molecular perspective
Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.
research A split scalp study to evaluate the effects of platelet rich plasma prepared by two different methods in androgenetic alopecia
research 186 Dissecting the role of the common neurotrophin receptor CD271 in the skin: generation and characterization of a novel mouse model with keratinocyte-specific conditional deletion
Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.
research H3K4me3 regulates the transcription of RSPO3 in dermal papilla cells to influence hair follicle morphogenesis and development
H3K4me3 helps control RSPO3 to influence hair growth and development.
research Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases
Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
research GPCRs as key regulators in wound healing
G-protein-coupled receptors (GPCRs) are crucial in the wound healing process, influencing immune cell recruitment and signaling pathways like Hedgehog-GLI, Hippo-YAP1, and Wnt/β-catenin, which are involved in epidermal cell proliferation and differentiation. By modifying GPCR activity with agonists or antagonists, it is possible to impact immune cell infiltration, inflammatory mediator production, and the rate of wound healing. This review discusses the fundamental mechanisms of GPCR signaling in wound healing and recent discoveries about their roles and functions.
research 085 Post-translational regulation of hair keratins in transfected COS-1 cells
research PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia
PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
research Progression of Pseudolymphoma to true Cutaneous lymphoma, possible role of Platelet-rich plasma (PRP), a case report.
PRP treatments and hair transplantation may be linked to the progression of pseudolymphoma to lymphoma.
research Genetic effects of vascular endothelial growth factor and its receptor 2 on feather maturity in three chicken breeds
VEGF and VEGFR-2 genes influence feather maturity, and specific genetic markers can improve chicken breeding.
research Evaluation of Not-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems
PRP treatment improves hair growth, and the device used can affect results, with some being more effective.
research Longitudinal biomarker trajectories accompanying trichoscopic change after PRP-based regimens for alopecia: a complementary multi-marker analysis of a real-world cohort.
PRP-based treatments can increase hair density, but results vary among individuals.
research Platelet-rich plasma: The journey so far !
Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.
research Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism
The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
research Cerebellar hypoplasia, hypergonadotrophic hypogonadism, retinitis pigmentosa, alopecia, microcephaly, psychomotor retardation, and short stature: “D-CHRAMPS syndrome”
"D-CHRAMPS syndrome" is a newly identified condition with multiple severe symptoms.
research The Effect of EGR1 on the Proliferation of Dermal Papilla Cells
Increasing EGR1 levels makes hair root cells grow faster.
research PRP Application in the Treatment of Knee Osteoarthritis: A Comprehensive New Perspective in Light of Current Literature and Clinical Consensus Reports
PRP can help reduce pain and improve knee function in osteoarthritis, but more research is needed for consistent results.
research Effects of autologous platelet‑rich plasma injections on facial skin rejuvenation
PRP injections improve facial skin by reducing wrinkles and pores.
research Autologous Platelet-Rich Plasma Injection Therapy
PRP injection therapy shows promise for treating hair loss, increasing hair count and thickness with minimal side effects.
research Severe, Disfiguring, Pityriasis Rubra Pilaris in a Woman in the Dominican Republic
A woman with HIV had a severe skin condition that improved with antiretroviral therapy.
research Prediction of cell states and key transcription factors of the human cornea through integrated single-cell omics analyses
A new tool accurately identifies human cornea cell states and key factors.
research Effective high-throughput isolation of enriched platelets and circulating pro-angiogenic cells to accelerate skin-wound healing
Angio PRP speeds up skin wound healing and reduces inflammation.