research First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours.
ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.
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630-660 / 1000+ resultsresearch A Productive Black Facial Pore
A man had a black pore on his cheek, which was removed and found to be a hair follicle tumor.
research Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations
Disrupting β-catenin signaling in certain cells causes anorectal malformations.
research Kerion celsi due to Microsporum audouinii: a severe form in an immunocompetent girl
A 9-year-old girl with a healthy immune system was successfully treated for a severe fungal scalp infection caused by Microsporum audouinii.
research Decision letter: NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures
NuMA-microtubule interactions are vital for proper skin structure formation and function.
research PLCD1 and Pilar Cysts
The research linked PLCD1 gene variants to the development of trichilemmal cysts.
research Hair disorder in dr. Cipto Mangunkusumo cosmetic dermatology and venereology outpatient clinic of Jakarta, Indonesia: A socio-demographic and clinical evaluation
Most hair disorder patients at the clinic were young adult males, with alopecia areata being the most common condition.
research Biosynthetic studies through feeding experiments in Eclipta prostrata (L.) L. hairy roots
The study found that in Eclipta prostrata roots, coumestans come from acetate and shikimate pathways, and phenylpropanoid is made only through the shikimate pathway.
research JUNB affects hair follicle development and regeneration by promoting the proliferation of dermal papilla cells in goat
JUNB boosts hair growth in goats by helping specific skin cells multiply.
research The Negative Regulator CXXC5: Making WNT Look a Little Less Dishevelled
CXXC5 is a protein that prevents hair growth and could be a target for hair loss treatment.
research Central centrifugal cicatricial alopecia in Black men: A case series highlighting key clinical features in this cohort
The document concludes that early and accurate diagnosis of hair loss on the top of the scalp in Black men is important to distinguish CCCA from other types of hair loss.
research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation
HOXC13 is essential for hair and nail development by regulating Foxn1.
research Kerion Celsi due to Microsporum canis in an Adult Woman, Treated Successfully with Fosravuconazole
Fosravuconazole effectively treated a woman's scalp infection without side effects.
research [Peptidergic innervation in the sinus hair follicles of several mammalian species].
Sinus hair follicles in mammals have different nerve fiber types with species-specific patterns, especially in cats.
research ROS-Scavenging CuxO Nanozyme-Functionalized Microneedle Patch for Androgenetic Alopecia Treatment
The microneedle patch with CuxO nanozymes effectively promotes hair growth for treating hair loss.
research Scalp Micropigmentation for Camouflage of Cicatricial Alopecia From Lichen Planopilaris
research Hair Shaft Abnormalities. Pili Bifurcati: A Scanning Electron Microscopy Analysis
The study found that pili bifurcati causes hair to intermittently split into two branches, each with its own outer layer.
research Skin morphology of the mutant hairless USP mouse
Hairless USP mice have enlarged skin cysts as they age.
research H15 Inflammation of the hair follicle: multiple eponyms!
Hidradenitis suppurativa has had many names, but its naming is still not agreed upon.
research Pitfalls of overzealous iconodiagnosis of the Girl with a Pearl Earring
Vermeer likely omitted eyebrows for style, not due to hair loss.
research Effects of Hura crepitans and Its Active Ingredient, Daphne Factor F3, on Dihydrotestosterone-Induced Neurotrophin-4 Activation and Hair Retardation
Hura crepitans and its compound daphne factor F3 may help treat hair loss by blocking a specific hair growth inhibitor.
research Multiple, hereditary dome-shaped papules and acrochordons. Birt-Hogg-Dube syndrome
The boy likely has a fungal infection causing hair loss.
research 520 The protective effects of Apocynin against ultraviolet B-induced cellular senescence in human keratinocytes
Apocynin may protect skin cells from aging and damage caused by UVB light.
research Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas.
Basal-cell epitheliomas and the pilosebaceous tract share a unique keratin, distinguishing them from other skin areas.
research An unusual variant of granulomatous adnexotropic cutaneous T-cell lymphoma
A rare type of skin lymphoma was identified, affecting hair follicles and sweat glands.
research P095 The Very Interesting Small Bowel Lesions of Cronkhite-Canada Syndrome
Small bowel lesions in Cronkhite-Canada syndrome persist despite steroid treatment.
research Leukemia cutis of the scalp masquerading as 'Kerion' in a child
Leukemia can sometimes appear as unusual skin issues in children.
research Dual Tumors — Trichoadenoma of Nikolowski and Melanocytic Naevi
A person had two different benign skin tumors, a trichoadenoma and melanocytic naevi, at the same time but in different places on the face.
research The cell membrane complex: Three related but different cellular cohesion components of mammalian hair fibers
The cell membrane complex in mammalian hair has three distinct types with different structures and chemical properties.
research Nestin is a marker of unipotent embryonic and adult progenitors differentiating into an epithelial cell lineage of the hair follicles
Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.