10 citations
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October 2016 in “Epilepsy & behavior” Levetiracetam often causes behavioral issues, while oxcarbazepine is more likely to cause sleepiness in epilepsy patients.
294 citations
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February 1994 in “PubMed” Valproic acid is an effective and safe first-choice treatment for many types of seizures.
55 citations
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December 1983 in “Acta Neurologica Scandinavica” Carbamazepine, valproate, and clonazepam can cause mild to serious side effects during long-term epilepsy treatment.
7 citations
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September 2007 Valproate sustained-release is effective and generally safe for short-term treatment of new partial epilepsy.
November 2014 in “Clinical Neurophysiology” High doses of progesterone can reduce seizures in mice.
16 citations
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February 2009 in “Clinical neurology and neurosurgery” Switching to extended-release divalproex sodium improved patient-reported tremor but did not change seizure frequency or most side effects.
35 citations
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August 2004 in “Epilepsy & behavior” Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.
Sodium valproate improved epilepsy control in most children but often caused weight gain and other mild side effects.
1 citations
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April 2011 in “The FASEB Journal” Progesterone-derived neurosteroids affect GABA-A receptor expression, influencing epilepsy during menstrual cycles.
26 citations
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November 2013 in “Neuroscience” Progesterone can reduce seizures without relying on the GABAA receptor pathway.
June 2014 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” Progesterone and its metabolites can prevent seizures without major side effects.
January 2004 in “Data Archiving and Networked Services (DANS)” Finasteride blocks progesterone's effect on brain activity linked to epilepsy.
January 2017 in “SHILAP Revista de lepidopterología” Agomelatine might help reduce hair loss caused by valproate.
11 citations
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November 2011 in “Neuroreport” Paroxetine relieves pain by increasing allopregnanolone levels.
January 2004 in “Headache” Divalproex sodium significantly improved headaches in two-thirds of patients.
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February 2009 in “Pain” Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
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October 1976 in “Acta Neurologica Scandinavica” Sodium valproate reduced seizures in many patients with resistant epilepsy.
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February 2003 in “Annals of Neurology” Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
16 citations
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October 1994 in “PubMed” Sodium valproate is a safe and effective epilepsy drug with manageable side effects.
January 2025 in “Seizure” Dual anti-seizure medications, especially valproic acid with lamotrigine, often cause more side effects like hair loss and memory issues.
21 citations
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April 2011 in “Epilepsia” The drug combination significantly reduced epileptic drop attacks in patients.
13 citations
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September 1989 in “International Journal of Dermatology” Carbamazepine may cause reversible nail detachment.
64 citations
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March 1989 in “PubMed” Valproate is effective for epilepsy but has side effects and requires careful monitoring.
April 2024 in “Skin health and disease” Using a special skin cream with gabapentin helped reduce symptoms of a certain scalp condition but didn't change nerve fibers or skin chemicals.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Topical gabapentin was safe and effective for treating scalp symptoms and promoting hair regrowth in cicatricial alopecias.
2 citations
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February 2003 in “Annals of Neurology” Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
May 2024 in “Brain disorders” Agmatine may help reduce seizures linked to hormone changes in female rats.
38 citations
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November 2005 in “Epilepsia” Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.
May 2011 in “Psychiatric News” Horizant has risks like other seizure drugs, Johnson & Johnson misled about Risperdal, and Quanterix found a possible link between brain oxygen loss and Alzheimer's markers.
170 citations
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June 1974 in “BMJ” Sodium valproate effectively reduces seizures in epilepsy, especially in absences and myoclonic types, with minimal side effects.