May 2025 in “Journal of Diverse Medical Research Medicosphere” More research is needed to understand and manage angioedema in pregnant women with lupus.
724 citations
,
April 2004 in “Lancet Oncology” Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.
126 citations
,
October 1983 in “Journal of The American Academy of Dermatology” Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.
123 citations
,
May 2009 in “Journal of Neuroscience” In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
67 citations
,
July 2006 in “Clinics in Dermatology” Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.
43 citations
,
November 2007 in “Dermatologic Clinics” Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.
39 citations
,
May 2011 in “European Journal of Clinical Investigation” Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.
30 citations
,
May 1991 in “Psychosomatics” Some psychiatric medications can cause reversible hair loss.
29 citations
,
December 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.
19 citations
,
August 2016 in “Health and Quality of Life Outcomes” Metformin helped improve the quality of life for Chinese women with PCOS, especially in physical health and symptoms like infertility, acne, and hair loss.
16 citations
,
March 2018 in “Seminars in Oncology” The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
6 citations
,
March 2009 in “Annals of Saudi Medicine” Finasteride use during early pregnancy may cause limb deformities in babies.
5 citations
,
January 2020 in “in Vivo” Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
4 citations
,
November 2012 in “Obstetrics, Gynaecology & Reproductive Medicine” Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.
3 citations
,
June 2018 in “International Journal of Clinical Pharmacy” Baby born healthy despite mom taking finasteride, but more research needed.
1 citations
,
August 2023 in “Curēus” Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.
1 citations
,
August 2013 in “Springer eBooks” Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.
January 2018 in “Springer eBooks” Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
Metformin is safe in early pregnancy for women with PCOS and may reduce certain risks.
100 citations
,
May 2003 in “Journal of Neuroscience” Neuroactive steroids affect cocaine's rewarding effects through the ς1 receptor.
1 citations
,
May 2017 in “Asian journal of medical sciences” The dietary supplement significantly improved skin, nails, and hair in older adults.
January 2026 in “Frontiers in Reproductive Health” Educational efforts can reduce harmful chemical exposure from hair products in pregnant Women of Color.
July 2025 in “UCP Journal of Science & Technology” Certain blood and kidney tests can indicate pregnancy.
March 2022 in “Pakistan BioMedical Journal” Many young women in Pakistan are unaware of their PCOS symptoms.
73 citations
,
March 2014 in “Journal of The American Academy of Dermatology” Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.
4025 citations
,
December 2003 in “Human Reproduction” The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
12 citations
,
April 2018 in “Physiology & Behavior” Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.
12 citations
,
April 2016 in “PLoS ONE” The Chi-PCOSQ is effective for assessing health-related quality of life in Chinese women with PCOS.
4 citations
,
July 2021 in “Cancer Research and Treatment” Temozolomide improves survival in grade III glioma patients without harming quality of life.