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The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.

Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.

During late pregnancy in rats, hormonal changes increased certain GABAA receptors in specific brain cells.

Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

A new method effectively predicts estrogen-related health effects for early screening.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

Paxillin may help manage androgen-related disorders like PCOS by stabilizing androgen receptor proteins.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Neurosteroid withdrawal increases α4 subunit expression in the hippocampus, which may relate to catamenial epilepsy in women.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Changing Allopregnanolone levels in newborns affects adult behavior and anxiety.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.

Finasteride and DEHP exposure during development can change reproductive markers in rats.

Pharmacophore models can predict liver toxicity and central nervous system toxicity, but they have limitations and specific requirements.

Neogynon effectively prevents pregnancy but may cause side effects like headaches and menstrual changes.

A new compound was made that might help treat diseases related to male hormones.

Paternal drug exposure can harm fertility, pregnancy outcomes, and offspring health, with specific drugs linked to various reproductive issues.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Reduced neurosteroids and growth issues can harm fetal brain development, especially in males.

More research is needed on the safety of fathers' drug exposure before conception.

Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.

The piRNA pathway genes are crucial in early development and may influence sex differentiation through hormone regulation.

Progesterone and its metabolites can prevent seizures without major side effects.