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Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.

Allopregnanolone likely doesn't influence ethanol's rewarding effects in these mice.

Finasteride blocks progesterone's effect on brain activity linked to epilepsy.

The new compounds may be more effective and cheaper than current treatments for conditions like baldness.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Progesterone and its metabolites can prevent seizures without major side effects.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Progesterone reduces anxiety without needing progesterone receptors.

Allopregnanolone affects fear responses differently in male and female rats, possibly explaining sex differences in anxiety disorders.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.

Allopregnanolone may help reduce inflammation and symptoms related to post-finasteride syndrome.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.

Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

High doses of progesterone can reduce seizures in mice.

Progesterone affects GABA_A receptor function by altering δ subunit levels.

A new compound was made that might help treat diseases related to male hormones.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Reduced neurosteroids and growth issues can harm fetal brain development, especially in males.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.