December 2020 in “Current Sexual Health Reports” Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
July 2017 in “Contemporary Endocrinology” The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
January 2017 in “Elsevier eBooks” Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
January 2016 in “Research Explorer (The University of Manchester)” Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.
November 2013 in “John Wiley & Sons, Ltd eBooks” The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
May 2010 in “Current Women's Health Reviews” The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.
February 2010 in “ePrints Soton (University of Southampton)” Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
January 2008 in “Pratique médicale & chirurgicale de l'animal de compagnie” Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.
January 2007 in “Acta Veterinaria Brno” Trilostane treatment successfully restored hair growth in a dog with alopecia X.
November 2004 in “John Wiley & Sons, Ltd eBooks” Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.
June 2003 in “Obstetrical & Gynecological Survey” After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.
June 2003 in “Obstetrical & Gynecological Survey” Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.
123 citations
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May 2009 in “Journal of Neuroscience” In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
61 citations
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January 2008 in “Biological & Pharmaceutical Bulletin” Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.
27 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.
1 citations
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August 2002 in “Zeitschrift für Hautkrankheiten” Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
Encapsulating hair loss drugs in cyclodextrins improves their solubility and reduces scalp irritation.
November 2016 in “Elsevier eBooks” Genetic mutations can affect female sexual development, requiring personalized medical care.
14 citations
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July 1987 in “Dermatologic Clinics” The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.
3 citations
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May 1990 in “Journal of Steroid Biochemistry” Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.
January 2020 in “Proyecto de investigación:” Longer anogenital distance may indicate a higher chance of having polycystic ovary syndrome, and measuring this distance along with hormone levels could improve diagnosis.
289 citations
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May 2003 in “Journal of Investigative Dermatology” Human skin can produce steroids from cholesterol.
22 citations
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January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” A new method accurately measures nine specific hormones in human blood.
14 citations
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May 2005 in “Steroids” A new method was developed to make finasteride for treating hair loss.
70 citations
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September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
16 citations
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June 2022 in “Journal of Pediatric Endocrinology and Metabolism” Reducing phthalate exposure may help prevent early puberty in girls.
5 citations
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September 2012 in “BMJ case reports” Ashwagandha may improve hormone levels and reduce hair loss in non-classical adrenal hyperplasia.