30 citations
,
April 2009 in “Mycoses” Microsporum gypseum fungus breaks down keratin in hair by digesting it enzymatically, starting with less keratinized parts.
June 2025 in “Advances in Clinical and Experimental Medicine” Keratin biomaterials could help heal wounds and regenerate tissue, but more testing is needed.
December 2025 in “American Journal of Dermatopathology” Keratin 19 may help diagnose and treat certain types of permanent hair loss.
November 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Keratin 79 cells help form and regenerate hair canals.
30 citations
,
December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
March 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Beard hair medulla cells have a unique and varied keratin pattern.
12 citations
,
June 2013 in “International Journal of Dermatology” Seborrheic keratosis shows varied cell differentiation, and keratin analysis helps diagnose skin tumors.
63 citations
,
July 2006 in “British Journal of Dermatology” Psoriasis causes changes in certain keratins and shrinks sebaceous glands in the scalp.
29 citations
,
August 2011 in “PubMed” Hair and nail proteins, mainly keratins, are crucial for structure and can indicate health issues.
17 citations
,
November 2000 in “Journal of Investigative Dermatology” ZPK helps skin cells mature and may affect skin health.
28 citations
,
November 1987 in “Journal of the American Academy of Dermatology” The model successfully grew and differentiated hair follicle cells in the lab.
28 citations
,
January 1997 in “Elsevier eBooks” Keratinocyte stem cells help regenerate and repair cornea, skin, and hair.
13 citations
,
March 1997 in “Research in Veterinary Science/Research in veterinary science” Epithelial proliferation and hyperkeratosis are linked to gastric ulcers in pigs.
135 citations
,
October 1997 in “Journal of biological chemistry/The Journal of biological chemistry” Trichohyalin is modified by enzymes to form strong structures in hair cells.
14 citations
,
January 2021 in “Stem cell research & therapy” Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.
22 citations
,
February 2012 in “Journal of Investigative Dermatology” A specific gene mutation causes severe skin and nail issues and hair loss.
6 citations
,
December 1990 in “PubMed” Keratinocytes in hair follicles differentiate similarly to skin cells, with specific patterns in different regions.
3 citations
,
January 1989 in “The Nishinihon Journal of Dermatology” A hair cyst can become cancerous, showing specific keratins from the hair sheath.
1 citations
,
June 2009 in “WakeSpace (Wake Forest University)” Keratin biomaterials can effectively aid peripheral nerve regeneration and improve recovery.
1 citations
,
July 2006 in “Journal of Investigative Dermatology” A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.
9 citations
,
July 2008 in “Archives of Dermatological Research” January 2026 in “International Journal of Biological Macromolecules” Keratin in people with androgenetic alopecia shows specific changes that could help develop new treatments.
30 citations
,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
18 citations
,
June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
68 citations
,
August 2014 in “PeerJ” Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.
3 citations
,
December 2013 in “Journal of Cell Science” Keratin 79 cells help form and regenerate hair canals.
8 citations
,
August 1993 in “Colloid & Polymer Science” The observed "toughening" in keratin was actually due to water evaporation, not a real change in keratin.
1 citations
,
October 2022 in “Scientific reports” Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.
124 citations
,
December 1988 in “Differentiation” Trichocytic differentiation starts in cells with epithelial cytokeratins, transitioning to trichocytic cytokeratins in hair and gradually in nails.
A new hydrogel made from human hair keratin can help regenerate skin and fight bacteria.