July 2007 in “Journal of Generic Medicines” The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.
249 citations
,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
82 citations
,
January 2002 in “Journal of drug targeting” Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
66 citations
,
September 1982 in “Biochemical Pharmacology” Liver enzyme helps minoxidil work better for blood vessel relaxation.
64 citations
,
June 2020 in “PLoS ONE” Red light boosts beneficial compounds in Eclipta alba cultures.
61 citations
,
April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
60 citations
,
December 2005 in “Biomedical Papers” Hair analysis can detect drug use but requires careful interpretation due to its complexity.
59 citations
,
January 2015 in “Nanoscale” The new micelle formulation delivers acne treatment more effectively and safely than current gels.
41 citations
,
March 2007 in “Steroids” New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
33 citations
,
November 2008 in “European Journal of Pharmaceutical Sciences” St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
31 citations
,
October 2020 in “Journal of nanomaterials” Silver nanoparticles made from Grewia optiva leaf extract show strong antibacterial, antioxidant, and hair growth benefits.
30 citations
,
December 2019 in “PLoS ONE” The new delivery system improved raloxifene's skin absorption and effectiveness against cancer cells.
28 citations
,
November 2020 in “Journal of Controlled Release” A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
27 citations
,
June 2015 in “Journal of photochemistry and photobiology. B, Biology” The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
27 citations
,
May 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
27 citations
,
April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
25 citations
,
February 1989 in “The Journal of Clinical Pharmacology” This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.
24 citations
,
April 2007 in “European Journal of Pharmaceutics and Biopharmaceutics” Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
23 citations
,
October 2006 in “Journal of Dermatological Science” Ethosomal minoxidil improves hair growth by penetrating deeper into skin and shortening hair cycle.
23 citations
,
January 2003 in “Journal of Pediatric Endocrinology and Metabolism” About 15% of US Army personnel use hair products containing hormone or placenta, with higher usage among non-whites, females, and enlisted personnel.
21 citations
,
January 1995 in “Journal of the American Institute for Conservation” A new method extracts red dyes from wool without damaging it, although it slightly weakens the wool.
21 citations
,
September 1977 in “Journal of Pharmaceutical Sciences” Minoxidil levels measured in human blood.
20 citations
,
December 2011 in “Journal of inherited metabolic disease” Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.
20 citations
,
January 2009 in “Chemical Papers” Both HPSAM and PLS methods accurately measure minoxidil and tretinoin concentrations.
18 citations
,
February 2023 in “PLoS ONE” A new triple drug system using nanoparticles effectively targets breast tumors in 3D models.
17 citations
,
May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine” Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
16 citations
,
August 2004 in “Tetrahedron” Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
15 citations
,
November 2017 in “Drug Development and Industrial Pharmacy” Improved tablets lead to faster, better drug absorption for hair loss treatment.
15 citations
,
December 2016 in “Advanced Pharmaceutical Bulletin” The new cream with N-acetyl glucosamine didn't change skin color after 8 weeks.