24 citations
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February 2007 in “Hormone and metabolic research” The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.
March 2025 in “Frontiers in Cell and Developmental Biology” Improving nerve and immune interactions may help heal chronic wounds.
January 2012 in “heiDOK (Heidelberg University)” Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.
91 citations
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August 2019 in “Frontiers in Microbiology” RpoS helps Borrelia burgdorferi survive in hosts and adapt to different environments.
17 citations
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October 2006 in “Molecular and Cellular Endocrinology” The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
December 2025 in “Frontiers in Immunology” Restoring nerve-macrophage communication may help treat autoimmune diseases.
10 citations
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February 2021 in “PLoS biology” Corin helps control salt and sweat release in sweat glands.
34 citations
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June 2011 in “Alcoholism: Clinical and Experimental Research” Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
March 2025 in “Journal of Cosmetic Dermatology” Botulinum toxin type A may widen certain arteries, but more research is needed.
July 2024 in “Journal of Investigative Dermatology” Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
32 citations
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August 1996 in “Journal of Investigative Dermatology” 8 citations
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August 2015 in “Endocrine”
Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.
May 2024 in “The journal of sexual medicine” Finasteride treatment may cause erectile dysfunction, but stopping it reverses these effects.
Adding a zygomaticotemporal nerve block reduces pain more effectively during hair regrowth treatments.
June 2003 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” GLABRA2 represses root hair formation by inhibiting a specific gene.
Thymosin β4 helps with healing, inflammation, and organ protection.
5 citations
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January 2023 in “Nature cell biology” A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
March 2026 in “Preprints.org” Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.
45 citations
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August 2018 in “Journal of Lipid Research” Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
5 citations
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January 2014 in “Molecular Simulation” A new compound may treat benign prostatic hyperplasia better than finasteride.
15 citations
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September 2018 in “Hearing research” Rapamycin reduces age-related hearing cell loss in mice, but acarbose does not.
40 citations
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March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
Finasteride may cause memory problems by damaging the hippocampus.
2 citations
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February 2021 in “Brain Research” Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
February 2025 in “Ciencia Latina Revista Científica Multidisciplinar” Finasteride can help with hair loss and prostate issues but may negatively affect mood and the nervous system.
51 citations
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July 2013 in “Brain Research” Testosterone needs to be converted to DHT to reduce stress response in male rats.
55 citations
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March 2005 in “Neuropharmacology” A neurosteroid can reduce caffeine-induced anxiety in rats.