10 citations
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January 1925 in “Archives of Dermatology” Trichostasis spinulosa is a rare skin condition with hair-filled plugs in hair follicles.
April 2024 in “Asian Journal of Medical Sciences” Ring block anesthesia is best for comfort and acceptance in PRP hair loss treatments.
124 citations
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December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
2 citations
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March 2024 in “Pharmaceutics” The placebo microneedle stamp didn't penetrate skin and caused less pain, but blinding was only effective for those with low skin sensitivity.
21 citations
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November 1969 in “Journal of Investigative Dermatology” A new staining method clearly shows nerves around eyebrow hair follicles.
1 citations
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July 2016 in “Reactions Weekly” Finasteride can cause itching, burning, and other side effects that may not go away after treatment.
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March 2023 in “Tidsskrift for Den norske lægeforening” Keratosis pilaris is a common skin condition causing a bumpy texture, sometimes linked to other diseases, with various treatments available.
Certain drugs, especially those for eyes, bacterial infections, imaging tests, and skin conditions, are more likely to cause itching, with differences seen across gender, age, and weight.
46 citations
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April 1987 in “Brain Research” 13 citations
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January 2019 in “Journal of the American Academy of Dermatology” Pityriasis rubra pilaris significantly worsens quality of life more than many other health conditions.
April 2024 in “Indian dermatology online journal” A rare hair follicle disorder can cause itchy, bluish-black bumps on the body.
September 2024 in “Dermatologica Sinica” Ponatinib can cause a rare skin reaction that resolves with topical treatment and temporary drug discontinuation.
227 citations
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February 1989 in “The Journal of Comparative Neurology” CGRP-IR axons may help maintain and renew tissues.
5 citations
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August 2005 in “Anatomy and Embryology” Rat skin has a linear system of nerve fibers linked to hair follicles and muscles.
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June 2015 in “British Journal of Dermatology” A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.
15 citations
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October 2006 in “Journal of the American Academy of Dermatology” Liquid nitrogen spray caused a temporary, harmless swelling under the skin in an elderly woman.
20 citations
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January 2015 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.
July 2025 in “The Journal of Physiology” C-tactile afferents are linked to emotional touch and social bonding through hair movement.
7 citations
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September 2018 in “Journal of cosmetic dermatology” A patient had painful swollen lymph nodes after a cosmetic skin and hair treatment, suggesting doctors should warn about this risk.
1 citations
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April 2015 in “Neurology” Skin pigmentation increases in CRPS-affected areas and improves with symptom relief.
109 citations
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April 1997 in “Archives of Dermatological Research” Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.
3 citations
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October 2021 in “Dermatologic Therapy” PRP with microneedling improves hair growth and patient satisfaction more than injections for androgenetic alopecia.
101 citations
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August 2003 in “Journal of comparative neurology” Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.
4 citations
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September 2021 in “Frontiers in allergy” The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.
April 2016 in “Journal of Investigative Dermatology” Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.
1 citations
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August 2021 in “Pediatrics in review” A 10-year-old girl had genital pain from a small, red, crusty mass on her labia.
7 citations
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October 1992 in “PubMed” Sinus hair follicles in mammals have different nerve fiber types with species-specific patterns, especially in cats.
September 2024 in “Journal of Cosmetic Dermatology” Cold gel compresses are the best for pain relief during scalp microneedling.
80 citations
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December 1996 in “Pain” Disruption of glycinergic circuits increases pain sensitivity, suggesting new pain treatment options.
April 2018 in “Journal of Investigative Dermatology” Sensitive scalp has higher pH, more redness, abnormal sebum, and altered bacterial makeup.