June 2026 in “Dermatology and Therapy” Combining multiple ingredients is the most effective treatment for hyperpigmentation.
May 2026 in “Frontiers in Cell and Developmental Biology” Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
April 2026 in “Frontiers in Immunology” Blocking the CXCL12–CXCR4 axis may help treat hair loss in alopecia.
December 2025 in “Italian Journal of Anatomy and Embryology” Understanding embryologic layers improves skin disorder diagnosis and supports developing targeted therapies.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” Targeting specific cell interactions may help treat skin fibrosis.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Rhamnose may help hair growth and pigmentation, making it a potential treatment for hair loss.
June 2023 in “Research Square (Research Square)” Hyaluronic acid and polycaprolactone improve skin regeneration, with polycaprolactone having a stronger effect on healing and tissue repair.
January 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.
June 2020 in “Journal of Investigative Dermatology” Certain bacteria can enhance skin regeneration.
November 2009 in “Medical & surgical dermatology” The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.
November 2008 in “Medical & surgical dermatology” A device was made in 2008 to measure hair loss severity. Other findings include: frizzy mutation in mice isn't related to Fgfr2, C/EBPx marks preadipocytes, Cyclosporin A speeds up hair growth in mice, blocking plasmin and metalloproteinases hinders healing, hyperbaric oxygen helps ischemic wound healing, amniotic membranes heal wounds better than polyurethane foam, rhVEGF165 from a fibrin matrix improves tissue flap viability and induces VEGF-R2 expression, and bFGF enhances wound healing and reduces scarring in rabbits.
30 citations
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December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
22 citations
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December 2013 in “Molecular biology of the cell” ILK is essential for proper hair follicle development and structure.
11 citations
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October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
3 citations
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October 2020 in “Internatuinal Journal of Radiation Research” Gamma irradiation can stimulate hair growth by promoting new blood vessel formation.
5 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Platelet-rich Plasma Gel may help treat en coup de sabre scleroderma, improving symptoms and skin quality with minimal side effects.
1113 citations
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
521 citations
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January 1954 in “Physiological Reviews” Hair growth is cyclic and influenced mainly by local factors.
405 citations
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May 2007 in “Journal of The American Academy of Dermatology” Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.
108 citations
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November 2006 in “Phytomedicine” Green tea component EGCG could potentially promote human hair growth.
97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
80 citations
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January 1995 in “The American Journal of Medicine” Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
75 citations
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January 2011 in “Plastic and Reconstructive Surgery” The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.
63 citations
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October 2013 in “Dermatologic Surgery” Platelet-Rich Plasma (PRP) increases the number of new hair follicles and speeds up hair formation.
40 citations
,
June 2013 in “Molecular Pharmaceutics” The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
39 citations
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December 2011 in “PLoS ONE” Radiofrequency exposure can stimulate hair growth by increasing IGF-1 in hair follicle cells.
34 citations
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June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
33 citations
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December 2004 in “Differentiation” Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.