Search

for
Search:

Sort by

Research

360-390 / 1000+ results

K15 Promoter-Driven Enforced Expression of NKIRAS Exhibits Tumor Suppressive Activity Against the Development of DMBA/TPA-Induced Skin Tumors

research K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors

4 citations , October 2021 in “Scientific Reports”

NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

research Keratin 15 promotes a progenitor cell state in basal keratinocytes of skin epidermis

February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)”

Keratin 15 helps keep skin cells in a young, undifferentiated state.

research A new mutation Rim3 resembling Re den is mapped close to retinoic acid receptor alpha (Rara) gene on mouse Chromosome 11

76 citations , January 1998 in “Mammalian Genome”

research Novel mutations in the keratin-74 (KRT74) gene underlie autosomal dominant woolly hair/hypotrichosis in Pakistani families

40 citations , December 2010 in “Human Genetics”

research The parathyroid hormone-related protein as a regulator of normal tissue functions

4 citations , January 1994 in “Current Opinion in Endocrinology & Diabetes”

PTHrP regulates various normal body functions, including bone development, skin, and muscle function.

research Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue¹

4 citations , June 1998 in “The Journal of Clinical Endocrinology & Metabolism”

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

research Cloning and Characterization of a Mouse Type I Hair Keratin cDNA

41 citations , December 1988 in “Journal of Investigative Dermatology”

research Skin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation.

30 citations , June 1993 in “The Journal of Cell Biology”

The oncoprotein causes abnormal hair growth without increasing skin cancer risk.

research Keratins: Dynamic, flexible structural proteins of epithelial cells

13 citations , May 2001 in “Current problems in dermatology”

Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.

research Class III Peroxidases PRX01, PRX44, and PRX73 Control Root Hair Growth in Arabidopsis thaliana

19 citations , May 2022 in “International journal of molecular sciences”

PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.

Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells

research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.

August 1994 in “Molecular Endocrinology”

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

research Coexpression of Keratins Characteristic of Skin and Hair Differentiation in Nail Cells

23 citations , February 1993 in “Journal of Investigative Dermatology”

research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16

53 citations , September 1999 in “The journal of cell biology/The Journal of cell biology”

K16 can partially replace K14 but causes hair loss and skin issues.

research Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21

January 1993

The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.

research HtrA1L364P leads to cognitive dysfunction and vascular destruction through TGF‐β/Smad signaling pathway in CARASIL model mice

3 citations , July 2022 in “Brain and Behavior”

The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

research The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites

28 citations , January 2015 in “Journal of Cell Science”

PINCH-1 is crucial for skin cell adhesion and movement, working with EPLIN and ILK.

research 078 The transmembrane protein LRIG1 regulates receptor tyrosine kinases in skin development and homeostasis

September 2017 in “Journal of Investigative Dermatology”

LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.

research The human keratins: biology and pathology

1398 citations , May 2008 in “Histochemistry and Cell Biology”

Keratins are crucial for cell stability, wound healing, and cancer diagnosis.

research TRPS1 haploinsufficiency results in increased STAT3 and SOX9 mRNA expression in hair follicles in trichorhinophalangeal syndrome

2 citations , September 2016 in “Journal of Dermatological Science”

Reduced TRPS1 leads to increased STAT3 and SOX9 in hair follicles, affecting hair growth.

research CLK1 and its Effects on Skin Stem Cell Differentiation

1 citations , April 2010 in “Digital WPI”

CLK1 is needed for skin cells to become epidermal cells but not sebocytes.

research A new heterozygous frameshift variant in keratin 10 resulting in ichthyosis hystrix in a father and daughter

March 2023 in “JAAD case reports”

A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.

research Overexpression of parathyroid hormone-related protein in the skin of transgenic mice interferes with hair follicle development.

211 citations , February 1994 in “Proceedings of the National Academy of Sciences”

Too much parathyroid hormone-related protein in skin disrupts hair growth in mice.

research Decision letter: Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin

December 2014

ERK activation spreads between cells in mouse skin, linked to cell division and influenced by TPA and EGF receptors.

research Association of Autoimmune Regulator Gene Rs2075876 Variant, but Not Gene Expression with Alopecia Areata in Males: A Case–control Study

8 citations , October 2019 in “Immunological investigations”

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

research Sequence and structure based assessment of non-synonymous SNPs in hypertrichosis universalis

3 citations , April 2012 in “Bioinformation”

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.

research Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene

1 citations , January 1992 in “DNA sequence”

Researchers found a non-functional sheep keratin gene due to mutations.

← Previous page Next page →