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Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Targeting abnormal lung fluid metabolism could reduce COVID-19 deaths and ventilator use.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Avoiding certain nutrients and drugs may help manage pemphigus.

Artesunate is generally safe for severe malaria, but patients should be monitored for delayed anemia after treatment.

Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

*Acorus calamus* has many medicinal benefits but needs more safety research.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.