research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
JunB is crucial for maintaining healthy skin and hair follicles.
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research Characteristic Localization of Neuronatin in Rat Testis, Hair Follicle, Tongue, and Pancreas
Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.
research Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin
CRISPR-based tools improve understanding and treatment of skin development and conditions.
research Efficient In Vivo Targeting of Epidermal Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector Driven by the Keratin 5 Promoter
Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
research Diverse mechanisms for endogenous regeneration and repair in mammalian organs
Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
research Ectopic Expression of the nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research Keratin expression by corneal and limbal stem cells during development
Different types of cells in the eye express specific keratins at various stages of development.
research DNA Methylation as an Epigenetic Memory Keeper during Skin Development and Regeneration
DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in mice
Wnt signaling is vital for cell growth, development, and cancer research.
research Nerve dependence in tissue, organ, and appendage regeneration
Nerves are crucial for the regeneration of various body parts in many animals.
research Exploring the role of stem cells in cutaneous wound healing
Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
research Advances of Stem Cell Therapeutics in Cutaneous Wound Healing and Regeneration
Stem cells show promise in speeding up wound healing and tissue regeneration.
research Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling
Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
research Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors.
Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.
research Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
research GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells
GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
research Identification of Bulge Stem Cells in Mouse and Human Hair Follicles
Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
research Ca 2+ -mediated protein citrullination regulates proliferation in the regenerating and malignant CNS
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
research The role of translation in keratinocyte cell fate determination.
Translation levels actively determine keratinocyte cell fate.
research New insights into the functions of Cox-2 in skin and esophageal malignancies
Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.
research Tracing the cellular origin of cancer
Understanding where cancer cells come from helps create better prevention and treatment methods.
research Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34
CD34 is a marker for isolating stem-like cells in mouse hair follicles.
research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation
Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles
SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
research Cell cycle controls long-range calcium signaling in the regenerating epidermis
Calcium signaling in skin cells is crucial for communication and regeneration.
research Skin biology
Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
research Exploring Human Skin Aging at the Single-Cell Level
Middle-aged skin shows aging signs, and quercetin might help delay them.
research A transient dermal niche and dual epidermal programs underlie sweat gland development
Sweat gland development involves two unique skin cell programs and a temporary skin environment.