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A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

Progesterone protects brain cells by converting to allopregnanolone and involving GABAA receptors.

Progesterone helps adult male mice's brain cells survive and improves learning and memory.

Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.

Progesterone helps adult male mice grow more neurons and improves memory.

Progesterone protects rat brain cells by enhancing GABA A receptor activity.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

5α-reduced neurosteroids may help regulate glial cell differentiation.

Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Progesterone and testosterone protect brain cells from damage through specific pathways.

Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Progesterone boosts alcohol's effect on brain, finasteride counters it.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.