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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Progesterone and testosterone protect brain cells from damage through specific pathways.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Sex and stress steroids quickly change brain cell structures in the hippocampus.

Finasteride slows down motherly behavior in first-time pregnant rats.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.

Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.

Progesterone and allopregnanolone increase glycine release in rat brain cells.

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

High doses of progesterone can reduce seizures in mice.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

MESTSV is a rare tumor that is mostly benign but needs long-term monitoring due to potential recurrence.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Mutations in certain receptors can cause diseases and offer new treatment options.

Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.