Search

everythinglearnresearchcommunity

for

Search:↓

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

New compounds show promise for treating benign prostate hyperplasia with fewer side effects.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Differences in enzyme activity and androgen receptors in hair follicles may explain why hair loss appears differently in men and women.

A new compound may effectively inhibit the enzyme linked to BPH and hair loss.

5α-reductase enzymes are crucial in certain disorders, and while treatment advances exist, more research on SRD5A3 is needed.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Human beard hair follicles change testosterone into other related hormones, but don't much change androstenedione into testosterone.

Both drugs lower DHT levels, with GI198745 being more effective.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Glioblastoma cells can make androgens, which might help the tumor grow.

The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

21-hydroxylase deficiency causes hormone imbalances leading to various symptoms, and diagnosis involves clinical and genetic tests.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.

Testosterone in human pancreas cells boosts insulin production.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.