1039 citations
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February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
508 citations
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February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
401 citations
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January 2013 in “Postepy Dermatologii I Alergologii” The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
343 citations
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December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
281 citations
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January 2013 in “British Journal of Dermatology” Manage vitiligo with treatments, address emotions, and use camouflage techniques.
270 citations
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March 2012 in “Dermatologic Surgery” Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.
254 citations
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January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
252 citations
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February 2018 in “npj Regenerative Medicine” Understanding different species' regeneration can improve mammalian healing.
211 citations
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May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
179 citations
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July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
176 citations
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January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
159 citations
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December 2007 in “American Journal of Pathology” Stress-related substance P may lead to hair loss and negatively affect hair growth.
153 citations
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October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
146 citations
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May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
141 citations
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August 2018 in “Nature Reviews Microbiology” Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
137 citations
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April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
120 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
117 citations
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August 2019 in “Drug Design Development and Therapy” Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.
113 citations
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September 2005 in “Journal of Investigative Dermatology” Applying a special compound can promote hair growth without harmful side effects.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
107 citations
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December 2013 in “International Journal of Dermatology” The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.
97 citations
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April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
91 citations
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July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
91 citations
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December 2010 in “Stem Cells” Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.
89 citations
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January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
85 citations
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July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
85 citations
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January 2007 in “Journal of Drug Targeting” Liposomes better deliver minoxidil for hair loss treatment than niosomes.
84 citations
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January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.