92 citations
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September 2013 in “Journal of Investigative Dermatology” BMAL1 and Period1 genes can influence human hair growth.
March 2013 in “Molecular & Cellular Toxicology/Molecular & cellular toxicology” m-Aminophenol in hair dye can cause skin cell toxicity and stress responses.
160 citations
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April 2014 in “Drug discovery today” Melatonin helps regulate sleep and may aid in treating various health issues.
Some factors can either promote or inhibit hair growth.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MOF controls skin development by regulating genes for mitochondria and cilia.
Human hair color is determined by melanin types and genetic factors.
233 citations
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July 1997 in “PubMed” High levels of ornithine decarboxylase can cause tumors in mouse skin.
April 2016 in “Journal of Investigative Dermatology” Decreasing MIG6 can increase the movement and invasiveness of MEK-inhibited mutant NRAS melanoma, particularly when stimulated by EGF.
8 citations
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June 2009 in “British Journal of Dermatology” Human melanocytes in skin and hair follicles don't express keratin 16 or 6 naturally.
July 2024 in “Journal of Investigative Dermatology” Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
15 citations
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August 2014 in “Journal of dermatological science” Pueraria thunbergiana extract may help prevent hair from turning gray.
February 2025 in “International Journal of Molecular Sciences” Altered lipid pathways in diabetic women may cause premature greying.
21 citations
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January 2019 in “Experimental dermatology” Light therapy using helium-neon lasers can help restore skin color in vitiligo by promoting skin cell growth and movement.
17 citations
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May 2018 in “Journal of Biomedical Optics” Certain types of human hair might help ultraviolet rays reach and damage cells, possibly leading to melanoma.
1 citations
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September 2018 in “International journal of research - granthaalayah” Human hair medulla doesn't break down hydrogen peroxide, which may affect hair color formation.
1 citations
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February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A peptide from hair follicle stem cells promotes hair growth by activating specific skin cells.
April 2016 in “Journal of Investigative Dermatology” MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.
Melatonin affects cell growth differently based on its concentration.
July 2024 in “Journal of Cosmetic Dermatology” Hydrophilic melanin may help hair grow by improving blood flow and regeneration.
16 citations
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July 2016 in “Journal of Dermatological Science” Regenerated hairs can regain their color if the wound occurs during a certain stage of hair growth, and this process is helped by specific skin cells and proteins.
3 citations
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January 2005 in “Photochemistry and Photobiology” Protein kinase C epsilon may promote skin cancer development after UV exposure by affecting nearby cells.
26 citations
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September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
12 citations
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May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
1 citations
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July 2006 in “Journal of Investigative Dermatology” A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.
35 citations
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January 1981
8 citations
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August 2015 in “Journal of dermatological science” Rhododendrol in skin-whitening products can cause skin depigmentation and immune reactions.
April 2015 in “Dentistry 3000” Premature hair graying in the face may be influenced by genetics and environment.
August 2021 in “Journal of Investigative Dermatology” Adjusting polyamine levels could help treat skin disorders like psoriasis and skin cancer.
52 citations
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January 2005 in “International journal of experimental pathology” Melatonin may reduce skin damage caused by X-rays in rats.
19 citations
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December 2016 in “PLOS ONE” Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.