Search

for
Search:

Sort by

Research

420-450 / 1000+ results

4-(Alkylthio)- and 4-(Arylthio)-Benzonitrile Derivatives as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production

research 4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production

11 citations , March 2009 in “Bioorganic & Medicinal Chemistry Letters”

Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.

research Investigation of the mechanisms of progesterone protection following oxygen–glucose deprivation in organotypic hippocampal slice cultures

16 citations , November 2011 in “Neuroscience Letters”

Progesterone protects brain cells by converting to allopregnanolone and involving GABAA receptors.

research Pantolactams as androgen receptor antagonists for the topical suppression of sebum production

5 citations , September 2011 in “Bioorganic & Medicinal Chemistry Letters”

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

research Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy

23 citations , July 2003 in “Pharmacology, Biochemistry and Behavior”

Finasteride blocks progesterone's effect on absence seizures in rats.

research MICROBIAL OXIDATION OF FINASTERIDE WITH MACROPHOMINA PHASEOLINA(KUCC 730)

3 citations , November 2017 in “International Journal of Pharmacy and Pharmaceutical Sciences”

Progressive Sleep Apneas Respond to Medroxyprogesterone Acetate

research PROGRESSIVE SLEEP APNOEAS RESPOND TO MEDROXYPROGESTERONE ACETATE

May 1981 in “Inpharma (Balgowlah)”

Medroxyprogesterone acetate improved sleep apnea symptoms in some obese patients.

A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia

research A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia.

May 2023 in “PubMed”

Redensyl, saw palmetto, and biotin with platelet-rich plasma is a better treatment for hair loss than Procapil with platelet-rich plasma.

Evaluation of Topical Sodium Valproate-Loaded Nano Spanlastics Formulation Versus Minoxidil 5% in the Treatment of Female Pattern Hair Loss Using Transdermal Delivery: A Comparative Study

research Evaluation of Topical Sodium Valproate-Loaded Nano Spanlastics Formulation versus Minoxidil® 5% in The Treatment of Female Pattern Hair Loss Using Transdermal Delivery: A Comparative Study

January 2023 in “The Egyptian Journal of Hospital Medicine”

Topical Valproic acid and 5% Minoxidil both significantly increase hair count in Female Pattern Hair Loss, with similar side effects.

research Bimatoprost for Hair Loss: Initial Studies and Application

January 2014 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks”

Bimatoprost may help with hair loss.

research Novel anticonvulsive effects of progesterone in a mouse model of hippocampal electrical kindling

26 citations , November 2013 in “Neuroscience”

Progesterone can reduce seizures without relying on the GABAA receptor pathway.

research New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors

14 citations , June 2011 in “Steroids”

New compounds may help treat prostate issues without affecting androgen receptors.

research Valproate in the Treatment of Persistent Chronic Daily Headache. An Open Label Study

111 citations , February 1991 in “Headache The Journal of Head and Face Pain”

Valproate significantly improved headaches in two-thirds of patients.

research Latent hazard in PC and BPH patients referred to antiandrogens:PC aggressiveness and NE differentiation

January 2004 in “Anticancer Research”

Long-term antiandrogen use may increase aggressive prostate cancer risk.

$Finasteride for Treatment of Refractory Hemospermia: Prospective Placebo-Controlled Study$

research Finasteride for treatment of refractory hemospermia: prospective placebo-controlled study

13 citations , September 2011 in “International Urology and Nephrology”

Optimization of Anti-Hair Loss Cream Formula with Saw Palmetto Extract (Serenoa Repens) Using Propylene Glycol and Glycerol as Humectants: Application with Factorial

research Optimasi formula krim anti hair loss ekstrak saw palmetto [Serenoa repens] dengan propilen glikol dan gliserol sebagai humectant : aplikasi dengan faktorial

January 2007

The conclusion cannot be provided as the document content is not available.

research Finasteride: a 5 alpha-reductase inhibitor.

12 citations , January 1993 in “PubMed”

research Improved synthesis of finasteride

January 2005 in “Zhongguo yaowu huaxue zazhi”

The new method makes finasteride production cheaper and safer for industry.

research Editorial Comment

February 2019 in “Urology”

Generic drugs for benign prostatic hyperplasia can cost up to 500% more at chain pharmacies compared to independent ones.

research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications

23 citations , October 2008 in “Journal of medicinal chemistry”

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

(1R,2S)-4-(2-Cyano-Cyclohexyl-Oxy)-2-Trifluoromethyl-Benzonitrile, A Potent Androgen Receptor Antagonist For Stimulating Hair Growth And Reducing Sebum Production

research (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production

14 citations , August 2007 in “Bioorganic & Medicinal Chemistry Letters”

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.