research The cellular basis of mechanosensory Merkel-cell innervation during development
BMP signaling is essential for the development of touch domes.
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30-60 / 1000+ resultsresearch Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
research Joint Public Review: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
Meis2 is essential for touch sensation and nerve function in mice.
research The sensory innervation of primate facial skin. II. Vermilion border and mucosa of lip
Monkey lips have dense sensory nerves similar to those in other skin areas, explaining their sensitivity.
research eLife assessment: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
research Club-like receptors respond to light touch but not to whisking
Club-like receptors detect light touch but not whisking.
research Three-dimensional architecture and linearized mapping of vibrissa follicle afferents
Large-scale reconstructions enhance understanding of vibrissal sensory mapping in the brain.
research Spider joint hair sensilla: adaptation to proprioreceptive stimulation
Spider joint hair sensilla are adapted to sense movement during walking.
research A SUBPOPULATION OF ITCH RECEPTORS MARKED BY RET EXPRESSION
A new type of nerve cell involved in itch perception was discovered.
research TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons
TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
research Attraction of sensory fibers by Merkel cells during co-culture of sensory ganglia and hair follcies in collagen-gel
research Parosmia: Pathophysiology and Management
research The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons
Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
research Novel Technologies for Exploring the Skin–Brain Axis
Advanced technologies can improve understanding and monitoring of skin-brain interactions.
research Mechanical stimulation of human hair follicle outer root sheath cultures activates adjacent sensory neurons
Touching hair can activate nearby nerve cells through signals from the hair's outer layer.
research Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research Tactile innervation densities across the whole body
Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.
research Photosensory Function, Reception and Response in Human Skin
Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.
research Skin-type-dependent development of murine mechanosensory neurons
Mechanosensory neurons adapt to different skin types after birth.
research 689 Regional differences in scalp innervation: A pilot study of the healthy scalp
The back of the scalp has more nerve fibers than the front, which may explain why some people feel more sensitivity there.
research Robust coupling between the C‐tactile afferent and the hair follicle in humans
C-tactile nerves are sensitive to hair movement.
research Sensitive skin
Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.
research Correlation of monosynaptic field potentials evoked by single action potentials in single primary afferent axons and their bouton distributions in the dorsal horn
The study found that nerve signals are stronger when there are more connection points, but not necessarily denser, along the nerve's path in the spine.
research Receptor types in cat hairy skin supplied by myelinated fibers.
Cats' hairy skin has different touch receptors connected by myelinated fibers.
research Author response: Hair follicle epidermal stem cells define a niche for tactile sensation
Skin stem cells in hair follicles are important for touch sensation.
research Growth of Nerve Fibers to Merkel Cells Observed in Co-Culture of Sensory Ganglia and Sinus Hair Follicles
Merkel cells likely attract sensory nerve fibers.
research Beyond the Surface: Exploring the Mind-Skin Dynamics of Psychodermatology
An integrated approach involving dermatologists, psychiatrists, and psychologists is crucial for managing skin disorders linked to psychological factors.
research 50285 Oxytocin receptor is present in keratinocytes near touch and pain sensory neurons
Oxytocin receptors are found in skin cells near touch and pain neurons.
research Assessment of the Embryological Origin, Anatomical and Histological Structure of the Skin
The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.
research KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors
KCNQ potassium channels help control the sensitivity of touch receptors in the skin.