April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair growth cells and aiding self-repair.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair cells.
December 2019 in “Fayoum University Medical Journal” People with Alopecia areata have higher levels of prostaglandin D2 in their blood and tissues.
April 2019 in “Radiotherapy and oncology” HPV infection is linked to better survival in advanced anal cancer, higher radiation doses improve survival, especially in HPV-negative patients, and prostaglandin E₂ pretreatment can protect mouse hair follicles from radiation damage.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
April 2016 in “Plastic and reconstructive surgery. Global open” Tafluprost could be a potential treatment for hair loss by promoting hair growth phase changes.
April 2018 in “Radiotherapy and Oncology” Prostaglandin helps regenerate hair follicles after radiation damage.
1 citations
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March 2023 in “Frontiers in Medicine” Topical prostaglandin analogs may help with hair growth but more research is needed.
14 citations
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November 2009 in “Clinical and experimental dermatology” Topical prostaglandin E2 can help treat both alopecia areata and vitiligo.
April 2026 in “International Journal of Drug Delivery Technology” Topical prostaglandin analogues may improve hair density in androgenetic alopecia, but more research is needed.
9 citations
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January 2021 in “Mediators of Inflammation” 15d‐PGJ2 cream protects against UVB-induced skin damage in mice.
January 2026 in “International Journal of Biological Macromolecules”
397 citations
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February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
201 citations
,
May 2001 in “Proceedings of the National Academy of Sciences” Overexpression of COX-2 in mice skin causes abnormal skin and hair development.
91 citations
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August 2015 in “Anais Brasileiros De Dermatologia” Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.
72 citations
,
July 2014 in “American journal of clinical dermatology” Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.
66 citations
,
June 2018 in “International Journal of Women's Dermatology” No cure for female pattern hair loss, but various effective treatments exist.
55 citations
,
July 2016 in “Dermatologic Therapy” Multiple treatments work best for hair loss.
48 citations
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April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
47 citations
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August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
42 citations
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March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
41 citations
,
September 2003 in “Journal of Investigative Dermatology” Overexpression of COX-2 causes early hair loss in mice, but can be prevented with a COX-2 inhibitor.
40 citations
,
September 2019 in “Molecular and Cellular Endocrinology” Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
39 citations
,
April 2001 in “Journal of The American Academy of Dermatology” Latanoprost, a glaucoma medication, caused excessive eyelid hair growth in many patients.
35 citations
,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
35 citations
,
May 2012 in “Expert Opinion on Pharmacotherapy” The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.
31 citations
,
October 2010 in “Progress in lipid research” LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
24 citations
,
August 2017 in “Prostaglandins & Other Lipid Mediators” CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.
24 citations
,
January 2018 in “Indian Journal of Dermatology, Venereology and Leprology” Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.
22 citations
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April 2003 in “Eye” Applying latanoprost on skin can stimulate hair growth with minimal side effects.