Search

everythinglearnresearchcommunity

for

Search:↓

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

Higher SRD5A2 expression predicts better response to finasteride in treating urinary symptoms.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

Low-dose bisphenol A increases prostate size in rats by affecting certain enzymes.

SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

No link found between specific genes and female pattern hair loss.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.

Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.

mrp/plf-mRNA can indicate tumor-promoting effects in skin.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Progesterone affects GABA_A receptor function by altering δ subunit levels.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

Methylation of the 5-AR2 gene may cause resistance to Finasteride in BPH patients.

Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.