research Sulfatase inhibitors: a patent review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
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research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Pemphigus and associated comorbidities: a cross-sectional study
People with pemphigus are more likely to have conditions like hypothyroidism, inflammatory bowel disease, and diabetes.
research Finasteride-its impact on sexual function and prostate cancer
Finasteride reduces prostate cancer risk but may affect ejaculatory volume and requires careful consideration for young men.
research Alopecia and the metabolic syndrome
Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
research Androgenetic alopecia as an early marker of benign prostatic hyperplasia
Early hair loss may indicate prostate issues.
research Clinical Significance of Dense Fine Speckled Pattern in Anti-nuclear Antibody Test using Indirect Immunofluorescence Method
The dense fine speckled pattern in ANA tests is common in autoimmune diseases, challenging previous beliefs that it was unrelated.
research Alopecia and grey hair are associated with COVID‐19 Severity
Having a lot of gray hair and hair loss are linked to more severe COVID-19.
research Androgen antagonists in androgen target tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis
5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase
Scientists found new, better-working inhibitors for a hormone-related enzyme.
research COVID-19 and hypopituitarism
COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
research Lipid profile in patients with androgenetic alopecia: a meta-analysis
People with hair loss have worse cholesterol levels, possibly linking hair loss to heart problems.
research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors
Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
research Docking and Molecular Dynamics Identify Leads against 5 Alpha Reductase 2 for Benign Prostate Hyperplasia Treatment
New compounds show promise for treating benign prostate hyperplasia with fewer side effects.
research A machine learning and network framework to discover new indications for small molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Efectos adversos de finasteride: mitos y realidades. Una revisión actualizada
Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.
research Male pattern baldness and risk of colorectal neoplasia
Men with certain types of baldness at age 45 may have a higher risk of colon cancer and colorectal adenoma.
research Prostate volume and its relationship with anthropometric variables among different ethnic groups of South-Kivu, DR Congo
Prostate size varies by ethnic group, age, residence, and blood glucose, but not by body measurements or fat.
research The five-year effects of testosterone replacement therapy on lipid profile and glucose tolerance among hypogonadal men in Japan: a case control study
Testosterone replacement therapy improved blood sugar and fat levels without raising prostate cancer risk in Japanese men with low testosterone.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research Non-surgical management of BPH: An updated review of current literature and state of the art on natural compounds and medical therapy
Personalized treatment is crucial for effectively managing benign prostatic hyperplasia (BPH).
research Selenium Toxicity in Domestic Animals
Selenium can be toxic to animals, causing serious health issues, especially in horses.
research The Effect of Leonuri Herba alkaloids on Senile BPH (male and female hormone induced) model rats
Leonuri Herba alkaloids may help treat hormone-induced enlarged prostate in rats.
research The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells
SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.
research Telogen Effluvium
Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.
research Hydroxychloroquine modulates the progression of experimentally induced benign prostatic hyperplasia in rats via targeting EGFR/ERK/STAT3 and AR/FOXO1/TRAIL pathways: computational and in vivo studies
Hydroxychloroquine may help treat benign prostatic hyperplasia by reducing inflammation and promoting cell death.