research Finasteride for hair loss: a review
Finasteride helps hair growth but may cause sexual side effects and depression.
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research Updates in Treatment for Androgenetic Alopecia
New treatments for hair loss include low-dose oral minoxidil, light therapy, and innovative therapies targeting hair growth mechanisms.
research Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia
Finasteride doesn't effectively treat hair loss in postmenopausal women.
research Lack of effect of topical finasteride suggests an endocrine role for dihydrotestosterone
Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.
research Woolly Antics between the Sheaths
Lipase H is important for hair follicle function and shaping hair fibers.
research Androgenetic Alopecia
Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
research The effect of finasteride and dutasteride on the synthesis of neurosteroids by glioblastoma cells
Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
research Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development
Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
research Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD
Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
research HSD3B1 gene polymorphism and female pattern hair loss in women with polycystic ovary syndrome
HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.
research AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells
AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
research Subcellular localization of the five members of the human steroid 5α-reductase family
All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
research Ovine placental steroid synthesis and metabolism in late gestation†
Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men
Finasteride may lower cholesterol and slow heart disease progression.
research Actions of 5α-reductase inhibitors on the epididymis
5α-reductase inhibitors may reduce male fertility and could be used for male contraception.
research Cytologic Atypia in a 53-Year-Old Man With Finasteride-Induced Gynecomastia
research Managing patterned hair loss – a hair raising task!
Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.
research Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs
More personalized and effective treatments for androgenetic alopecia are needed.
research A microfluidic application for mass production of drug-loaded polymeric microspheres for a long-acting injectable with IVL-DrugFluidic®, a novel microfluidic microsphere manufacturing platform technology
IVL-DrugFluidic® can mass-produce high-quality, long-acting injectable drug microspheres, improving patient compliance and reducing side effects.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
research POST-FINASTERIDE SYNDROME AND POST-SSRI SEXUAL DYSFUNCTION: TWO CLINICAL CONDITIONS APPARENTLY DISTANT, BUT VERY CLOSE
Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
research Male infertility and genitourinary birth defects: there is more than meets the eye
Male infertility and genitourinary birth defects are often linked to genetic issues.
research Telomere Dynamics and Telomerase in the Biology of Hair Follicles and their Stem Cells as a Model for Aging Research
Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
research Saw palmetto and finasteride in the treatment of category III prostatitis/chronic pelvic pain syndrome
research Anti-nociceptive and anti-inflammatory properties of 5alpha-reductase inhibitor finasteride in experimental animals
Finasteride helps reduce pain and inflammation in animals.
research An appraisal of laboratory models of androgenetic alopecia: A systematic review
Better hair loss models needed for research.
research Finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles
Finasteride potentially treats hair loss by reducing DHT production.
research Inibição seletiva da 5α-redutase e preservação da aromatase no transplante capilar
A balanced approach using dutasteride and Serenoa repens can improve hair transplant success by protecting follicles and minimizing side effects.
research Abietic Acid from Resina Pini of Pinus Species as a Testosterone 5.ALPHA.-Reductase Inhibitor
Abietic acid from pine resin can effectively inhibit testosterone 5α-reductase.