12 citations
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December 2012 in “Current Drug Targets” The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
10 citations
,
May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
7 citations
,
March 2017 in “Medical Hypotheses” Aquaporins could be new drug targets for treating polycystic ovary syndrome.
7 citations
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March 2011 in “Hormone and Metabolic Research” Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.
6 citations
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March 2021 in “Journal of Cosmetic Dermatology” PRP injections promote hair growth and increase hair density in androgenic alopecia.
5 citations
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January 2017 in “Endocrinology” Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
3 citations
,
November 2015 in “Journal of Investigative Dermatology” Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
3 citations
,
October 2010 in “Epilepsy Currents” Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
February 2024 in “International journal of biology, pharmacy and allied sciences” Plant-based treatments can effectively and safely treat hair loss.
September 2023 in “Curēus” Reproductive hormones play a crucial role in breast cancer development and treatment challenges.
May 2022 in “Gastroenterology” Targeting NETs may help reduce fibrosis in Crohn's disease.
October 2010 in “Epilepsy Currents” Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.
December 2020 in “Journal of Aesthetic Nursing” Injecting platelet-rich plasma into the scalp stimulates hair growth, increases hair density, and treats hair loss effectively with minimal side effects.
October 2020 in “Journal of Aesthetic Nursing” Platelet-rich plasma (PRP) injections effectively treat hair loss and thinning in both men and women, with high satisfaction and no major side effects.
130 citations
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November 2017 in “Frontiers in Immunology” The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
1308 citations
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March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
18 citations
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October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
8 citations
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February 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
January 2023 in “Åbo Akademi University Research Portal” Vimentin is crucial for wound healing, cell growth, and managing immune responses.
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
January 2012 in “Durham e-Theses (Durham University)” Keratin 15 affects cell behavior and characteristics in skin cells.
86 citations
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December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
84 citations
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January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.
82 citations
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September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
47 citations
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July 2004 in “Journal of Dermatological Science” Hair loss in balding individuals is linked to changes in specific hair growth-related genes.
32 citations
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January 2021 in “Molecules” Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
13 citations
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January 2020 in “Neuroscience” Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
11 citations
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January 2022 in “Theranostics” Wnt4 is essential for heart repair and could be a target for heart disease treatment.
6 citations
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September 2012 in “Clinical Interventions in Aging” Honokiol might help reduce male skin aging by maintaining testosterone levels.