65 citations
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September 2014 in “BMC genomics” Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.
60 citations
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June 1997 in “Journal of The American Academy of Dermatology” Apoptosis is crucial for healthy skin and treating skin diseases.
54 citations
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January 2013 in “BMC Complementary and Alternative Medicine” Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.
53 citations
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January 2009 in “Journal of Investigative Dermatology” UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
52 citations
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April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
52 citations
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March 2010 in “British Journal of Dermatology” Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
49 citations
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March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
48 citations
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July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
47 citations
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December 2019 in “Biomaterials” Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
47 citations
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December 2019 in “Frontiers in immunology” A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
40 citations
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April 1999 in “Journal of Histochemistry & Cytochemistry” S100A3 protein is mainly found in specific parts of human hair cells.
39 citations
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January 2013 in “Journal of Investigative Dermatology” Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
38 citations
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June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
38 citations
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January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
30 citations
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November 2013 in “PLOS ONE” Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
28 citations
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March 2019 in “Journal of Dermatological Science” The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
28 citations
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November 2013 in “Cell and Tissue Research”
27 citations
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September 2017 in “Acta dermato-venereologica” Adults with certain skin conditions may have higher levels of inflammation in their body.
27 citations
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May 2011 in “Journal of Investigative Dermatology” TCHHL1 is a protein important for hair growth, found in hair follicles.
26 citations
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May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
25 citations
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August 2010 in “Acta Biomaterialia” Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
23 citations
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May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
23 citations
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May 2005 in “British Journal of Cancer” Plucked human hair can be used to study drug effects on certain cell markers.
22 citations
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November 2016 in “Indian Journal of Pharmaceutical Education and Research” Hibiscus rosa-sinensis leaf extract is safe, has strong antioxidants, and effectively heals wounds.
21 citations
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July 2004 in “Apmis” Fluorescent proteins help visualize and understand tumor blood vessel growth.
20 citations
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June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
19 citations
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January 2021 in “Experimental dermatology” Acne inversa is an epithelial-driven disease where inflammation is caused by cyst rupture, and treatments should focus on preventing tendril growth for better results.
19 citations
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January 2018 in “Scientific Reports” Non-immune factors play a significant role in alopecia areata.
18 citations
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December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
18 citations
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April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.