research Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis
Trps1 is essential for proper hair follicle development.
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research Skin Keratins
Keratins are important for skin cell health and their problems can cause diseases.
research Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression
Adipose-derived stem cells help heal radiation skin damage by reducing cell death and inflammation.
research Cryo-Electron Microscopy of Trichocyte (Hard α-Keratin) Intermediate Filaments Reveals a Low-Density Core
Trichocyte filaments have a low-density core and may include proteins for hair structure.
research Organization and Expression of Hair Follicle Genes.
Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.
research Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis
Trichohyalin is also found in the outer layers of normal human skin.
research Module-based complexity formation: periodic patterning in feathers and hairs
The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
research Hair growth inhibition by heparin in mice: a model system for studying the modulation of epithelial cell growth by glycosaminoglycans?
Heparin can inhibit hair growth in mice when injected.
research Embryonic keratinization in vertebrates in relation to land colonization
Keratinization in embryos helped vertebrates adapt to land by forming a protective skin barrier.
research Ultrastructural visualization of cross-linked protein features in epidermal appendages
Cross-linked proteins help maintain the structure of hair, feathers, and hagfish teeth.
research Effect of varied hair protein fractions on the gel properties of keratin/chitosan hydrogels for the use in tissue engineering
Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.
research Regulation of a hair follicle keratin intermediate filament gene promoter
The LEF-1 binding site enhances gene expression in hair follicles, with other proteins aiding specific regulation.
research Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes
FTase and GGTase-I are essential for skin keratinocyte health.
research Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology
Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.
research Epidermal Polarity Genes in Health and Disease
Disruptions in epidermal polarity genes can lead to skin diseases.
research Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas
Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.
research Evidence for various calcium sites in human hair shaft revealed by sub-micrometer X-ray fluorescence
The research found two types of calcium in human hair, one that varies among individuals and another that is consistent across people.
research The physical and chemical disruption of human hair after bleaching – studies by transmission electron microscopy and redox proteomics
Bleaching hair causes severe structural and chemical damage, including protein loss and oxidation.
research The structure of the “amorphous” matrix of keratins
Human hair keratin fibers have a detailed nano-scale structure that changes with different conditions.
research Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix
CIP/KIP proteins help stop cell division and support hair growth.
research Comparative proteomic analyses using iTRAQ-labeling provides insights into fiber diversity in sheep and goats
The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.
research EGF–FGF2 stimulates the proliferation and improves the neuronal commitment of mouse epidermal neural crest stem cells (EPI-NCSCs)
EGF–FGF2 helps mouse stem cells grow and become more like nerve cells.
research Proteomic analysis of hair shaft and nail plate.
Hair and nail proteins, mainly keratins, are crucial for structure and can indicate health issues.
research Identification and dissection of an enhancer controlling epithelial gene expression in skin
A specific DNA region controls skin cell gene expression by working with certain proteins.
research Protein disulphide isomerase-mediated grafting of cysteine-containing peptides onto over-bleached hair
PDI helps restore over-bleached hair's strength and structure by attaching special peptides.
research Inhibition of CCAAT/Enhancer Binding Protein Family DNA Binding in Mouse Epidermis Prevents and Regresses Papillomas
Blocking certain proteins in mouse skin can reduce and shrink skin tumors.
research Isolation of intermediate filament assemblies from human hair follicles.
Researchers isolated and identified structural components of human hair follicles, providing a model for studying hair formation.
research Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11
Two new gene clusters important for hair formation were found on human chromosome 11.
research Keratinization of sheath and calamus cells in developing and regenerating feathers
Feathers become harder as they develop due to a change in keratin type.
research Formation of regulator/target gene relationships during evolution
Gene regulatory regions evolve faster than protein coding regions, allowing new gene relationships without changing transcription factors.